832 
ANATOMY AND PATHOLOGY 
Figure 4. — Photomicrograph of lung in Figure 3. Mas- Figure 6. — Closer view of another cut surface of lung 
sive muscular hypertrophy is present in every pulmo- from case shovi'n in Figure 3. The air spaces are 
nary artery. Acid orcein Verhoeff, 11. 5x. raggedly enlarged. 
special techniques not normally used in routine 
autopsies. The lungs must be gently inflated 
with formalin or formalin vapors before cutting, 
and large thick sections are desirable. We have 
not used these techniques, and our 12 diagnoses 
of emphysema have been based on gross observa- 
tions of large doughy lungs, sometimes with 
bullous cysts, or on microscopic evidence of 
dilation of terminal air spaces and destruction 
of alveolar walls. Classification has not been 
attempted. 
Emphysema occurs in association with severe 
infestation with mites (Figs. 6, 7), but neither 
anatomical classification nor correlation with 
severity of parasitism or degree of arterial 
change has been made. Since the pathogenesis 
of the several kinds of pulmonary emphysema 
is controversial, macaques bearing lung mites 
If |- rv% M \ 
Figure 5. — Main pulmonary artery from lung in Figure 
3. The intima is uniformly thickened and contains 
numerous small elastic fibers. Acid orcein Verhoeff, 
42x. 
Figure 7. — Photomicrograph of lung in case shown in 
Figures 3 and 6. The air spaces are enlarged and 
simplified. Stubs of alveolar walls have terminal clubs 
of smooth muscle. Acid orcein Verhoeff, 50x. 
