G. D. HSIUNG AND N. S. SWACK 
963 
green monkeys studied, all of them possessed 
high levels of neutralizing antibody to a strain 
of African green monkey cytomegalovirus; 
whereas only lov^ levels of antibody titers were 
obtained in rhesus monkeys. Seroconversion 
of the rhesus monkeys to green monkey cyto- 
megalovirus occurred during captivity (Figure 
Ic). The origin of SV5 or parainfluenza 
5 virus infection in monkeys is as yet unclear.^i 
Monkey sera obtained at the site of capture did 
not contain SV5 antibody. In a study of 351 
paired sera collected from 161 green and 190 
rhesus monkeys during a 30-90 day quarantine, 
it was found that 45% of the rhesus and 56% 
of the green monkeys showed antibody conver- 
sion to SV5.^ Similar results were obtained by 
other investigators using either paired or 
single serum samples.22-24 it appears that mon- 
keys may have acquired SV5 infection after con- 
tact with man in a manner similar to that 
reported for measles virus infection in mon- 
keys^s (Figure Id). 
SUMMARY 
Longitudinal survey studies on virus infec- 
tions in "normal" healthy animals showed that 
a greater number of virus isolations were made 
from simian tissues than from the non-primate 
tissues. 
In the non-primate laboratory animals stud- 
ied, rabbit kidney cells were commonly found 
free of virus infection but the strain 2 inbred 
guinea pigs consistently harbored a herpes-like 
virus. 
In the domestic animal group, no virus was 
obtained from kidney cell cultures prepared 
from the 50 cattle examined but a herpesvirus 
was isolated from the kidney cultures of two of 
the ten horses examined. 
The virus types isolated from monkeys varied 
from time to time and laboratory to laboratory. 
Circulation of simian viruses occurred during 
( captivity. Green monkeys appeared to acquire 
SV40 and foamy virus type 1 from rhesus; 
whereas the latter apparently acquired cyto- 
megalovirus from green monkeys. Both mon- 
key species may contact SV5 from man. 
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