1064 
ANIMAL RESOURCES 
Table III 
A COMPARISON OF RANDOM SOURCE AND COLONY-BRED DOGS AND CANINE 
BLOOD ISSUES AT THE NATIONAL INSTITUTES OF HEALTH FROM 
FY 1964 THROUGH 1972 
Fiscal 
Random Source: 
Canine Blood: 
Colony Bred: 
Total 
Year 
Dogs 
% 
Dogs* 
% 
Dogs 
% 
1964 
4611 
100.0 
4611 
1965 
4532 
100.0 
4532 
1966 
4839 
100.0 
4839 
1967 
4398 
96.9 
133 
3.1 
4531 
1968 
3618 
94.2 
222 
5.8 
3840 
1969 
1861 
61.2 
860 
28.3 
320 
10.3 
3040 
1970 
1466 
42.9 
1620 
47.8 
328 
9.3 
3414 
1971 
965 
30.1 
1367 
42.7 
872 
27.2 
3204 
1972^ 
1060 
29.6 
1312 
36.7 
1210 
33.7 
3582 
Totals 
2"'350 
77.0 
5514 
15.4 
1210 
7.6 
35653 
* 1 dog = 2 units of blood 
t Dog and blood issues from July through December, 1971 multiplied by 2 
be recalled that the breeding and donor colonies 
are relatively permanent entities. 
The impact of blood issues from the donor 
colony on the random source and breeding pro- 
grams is shown in Table III. Blood issues are 
expressed in terms of dog-equivalents for ease 
in relating them to overall dog use. In addition 
to reducing random source dog issues, the blood 
donor program originally served to make facili- 
ties available for expanding the breeding colony 
to its present size. The firm establishment and 
continued enlargement of the breeding colony is 
expected to further reduce the need to quaran- 
tine and condition random source dogs. 
Research institutions concerned with reduc- 
ing the numbers of dogs required to meet their 
program needs and with increasing the quality 
of the dogs used might consider adapting either 
or both of the alternatives described above. The 
ultimate suitability of instituting either blood 
donor or canine breeding activities will, of 
course, depend on the specific requirements of 
the individual institution. 
REFERENCES 
1. Institute of Laboratory Animal Resources News, 
National Research Council — National Academy of 
Sciences. Vol. XII, No. 1: ii, 1968. 
2. Institute of Laboratory Animal Resources News, 
National Research Council — National Academy of 
Sciences. Vol. XIII No. 1 : iv, 1969. 
3. Institute of Laboratory Animal Resources News, 
National Research Council — National Academy of 
Sciences. Vol. XIV No. 2: vi, 1970. 
4. Jones, E. M. The laboratory animal welfare act: 
regulations, standards, enforcement, and progress. 
Journ. Amer. Vet. Med. Assoc. 153:1874-1877, 1968. 
5. ZiNN, R. D. The research dog. Journ. Amer. Vet. 
Med. Assoc. 153:1883-1886, 1968. 
6. Palmer, A. E. Disease problems encountered dur- 
ing conditioning of random source dogs and cats. 
Proceedings of the National Conference on Re- 
search Animals in Medicine, 1972. 
7. POTKAY, S., and Zinn, R. D. Effects of collection 
interval, body weight and season on the hemograms 
of canine blood donors. Lab. Animal Care 
19:192-198, 1969. 
8. Fletcher, W. D., Herr, R. H., and Rogers, A. L. 
Survival of purebred Laborador retrievers versus 
pound dogs undergoing experimental heart valve re- 
placement. Lab. Animal Care 19:506-50°, 1969. 
DISCUSSION 
C. Stormont, School of Veterinary Medicine, 
Davis, California : Dr. Potkay, when you're fig- 
uring the cost of your dogs and your select 
breeding colony, do you figure in your own sal- 
ary, too ? 
Dr. Potkay : Yes. 
Dr. Stormont: And all the caretakers? 
Dr. Potkay : Yes. 
Dr. Stormont : What was the cost over and 
above, say, random bred dogs? About $8 more? 
Dr. Potkay : Oh no. 
Dr. Stormont: Six? 
Dr. Potkay: This slide will give you an 
idea of what we do charge for these various 
dogs. 
Dr. Stormont: $22. 
Dr. Potkay : Right. 
Dr. Stormont: Well, what's the average 
price of your dogs over nine months old? Are 
they random source dogs ? 
Dr. Potkay: These are random source dogs 
that we issue and regardless of size or age, 
they're $99.50. 
Dr. Stormont : Most of those you're selling 
are all over nine months of age, aren't they? 
Dr. Potkay: No, a lot of them of various 
ages are used in this category. 
Dr. Stormont: I have one more question. 
Why do you exsanguinate random bred dogs 
when you bleed them, and don't exsanguinate 
your own dogs when you bleed them ? 
Dr. Potkay: We were never in the business 
of supplying blood at all until we initiated 
