W. S. TOPHAM 
AUTOMATIC MONITOR 
1225 
15 MINUTES 
DATA REDUCTION \ 
\ 
DATA 
SAMPLED 
1 
PROG 
1 
PROG 
2 
PROG 
3 
PROG 
4 
DATA 
SAMPLED 
2 
DATA 
SAMPLED 
6 
—3 SEC 
• 2.2 SEC ► 
Figure 6. — Functional diagram showing the operation of AUTOMON, the program which will automatically moni- 
tor the animals. 
the flow program gives a maximum and mini- 
mum reading simultaneously and stores all val- 
ues for future analysis. No digitization of oscil- 
lographic records is necessary. 
Pressure Pulse 
This program, using the method of Warner," 
calculates stroke volume from the central aortic 
pressure. With this information, it is possible to 
calculate cardiac output. The mean pressure is 
obtained as well as the systolic and diastolic 
pressure, and peripheral resistance can be cal- 
culated. Other variables which also are availa- 
ble in this program are stroke work, change of 
pressure with respect to time, dP/dT, and sys- 
tolic duration. This program does not use a trig- 
ger signal, but does a pattern recognition on the 
central arterial pressure waveform, and by find- 
ing the onset of systole, the peak pressure, the 
dicrotic notch, and the end of diastole, the above 
calculations are made. It would take many 
hours of calculation to obtain the information 
from the aortic pressure that the computer, 
using this program, is able to display within 
seconds. 
On-Line Data Review 
A program which functions in a different 
manner from the above programs is the 
On-Line Data Review, which is operated by use 
of the remote terminals. This program allows 
an experimenter at any time to review the data 
which has been obtained on any animal. The an- 
imal and device number are entered, and if all 
data is to be reviewed, then a display is called 
and the most recent information associated 
with that animal is displayed. The review then 
can proceed in a chronological manner, and by 
merely pressing a button, the data is displayed 
page by page or one measurement at a time, de- 
pending on the option selected. At any time, the 
operator can move ahead or backwards at hour 
intervals and review the data, or he can select a 
given time to the nearest hour when he would 
