Comparison of Blood-flow in the Hands. 
43 
cutaneously and by its stability, which resists heating to no 0 C, 
and which is not neutralized by adrenalin. 
B. It is possible that we have evidence here that the absence 
or the abnormal diminution of the adrenal secretion permits some 
of the pathogenetic action of the products and extracts of the 
tubercle bacillus and that their administration mixed with the 
whole adrenal or some part of it, in a measure overcomes their 
deleterious action. 
C. It is possible that the neutralizing value of blood mixed 
with tuberculin or some other appropriate adrenal antagonist 
might be a valuable index of the functional condition of the 
adrenal glands. 
25 (550) 
Comparison of the blood-flow in the hands in a case with lesion 
of upper motor neurones (birth palsy) and in a case with 
lesion of lower motor neurones (infantile paralysis). 
By G. N. STEWART. 
[From the Department of Experimental Medicine, Western Reserve 
University,] 
The blood flow was calculated from the formula 
H £ 
* ~ t - V X S 
where <p is the quantity of blood flowing through the hand in the 
period of observation, H the heat given off to a calorimeter con- 
taining the hand, T the temperature of the arterial blood coming 
to the hand (taken as rectal temperature) ,* T' the temperature of 
the venous blood leaving the hand (taken as the average tem- 
perature of the water in the calorimeter 2 ) and S the specific heat 
of blood. Before being put into the calorimeter the hand was 
immersed for a sufficient time (usually ten minutes) in a large 
Observations since made on the actual temperature of the arterial blood show 
that in a healthy man the rectal temperature is about half a degree above that of 
the blood coming to the hand under the conditions of the experiments. The tem- 
perature of the arterial blood is arrived at by determining that temperature of the 
calorimeter at which the hand neither loses nor gains heat. 
2 That this assumption is approximately correct for a certain range of bath tem- 
perature has been shown by actual measurement of the temperature of blood issuing 
from one of the veins of the hand, with suitable precautions to render the loss of 
heat as small as possible. 
