30 
Scientific Proceedings (41). 
the originally distal end of the stem, regardless as to whether the 
distal or proximal end of the stem had been directed centrifugally 
or centripetally in the experiment and regardless of the fact, that 
as in the higher speeds, the contents of the perisarc tube were 
compressed into the end of this tube which was directed centrifu- 
gally in rotation. This compression varied with the centrifugal 
force involved, but at the higher speeds, the contents which filled 
the tube for a distance of four centimeters, would be compressed, 
in the experiment, into a space measuring about five millimeters. 
When regeneration took place, the red pigment which marks the 
future hydranth pole could be seen collecting in the compressed 
protoplasm and gradually it migrated up the tube of perisarc 
until it reached the end of this tube, whereupon the tentacles 
and other parts of the normal hydranth appeared. 
That the red pigment has no r61e as a "formative stuff" has 
already been shown by Morgan according to evidence derived 
from another method of approaching the point and the present 
set of observations appears to show that if any stratification of 
"formative stuffs' ' occurs in the normal stem of the hydroid, 
whereby hydranth forming stuffs and stolon forming material are 
relegated to their respective ends of the stem, these stuffs are 
not responsive to the action of centrifugal force in the degrees 
used in the experiments or else they become rearranged when the 
centrifugal action has ceased. The generalization may be made 
that polarity in Tubularia crocea cannot be altered by the action 
of centrifugal force, in shifting "organbildende Bezirke" from one 
end of the hydroid stem to the other. 
17 (542) 
Oreatin and creatinine metabolism during convalescence 
after typhoid fever. 
By NELLIS B. FOSTER. 
[From the Wards of the New York Hospital and the Laboratory of 
Biological Chemistry of Columbia University at the College of 
Physicians and Surgeons, New York.] 
On account of the apparently intimate connection between 
"muscle efficiency" and the output of creatinine in human urine 
