Glycogenolytic Strength of Blood Serum. 19 
WXLRXS=red 9 long wings 
WSWXL =white d 1 " 
WSWXS= " " short 44 
WSRXL=red 44 long 44 
WSRXS= 4 4 4 4 short 44 
Note added November 20. 
The converse cross, viz., short- winged, white males by long- 
winged, red females gives also in the second generation besides 
long-winged, red- or white-eyed, males and females, short-winged 
red- or white-eyed males. 
Heterozygous white females (WXLWXS) by short-winged red 
males gives long-winged red females, short-winged red females, 
long-winged white males and short-winged white males. 
13 (538) 
The glycogenolytic strength of blood serum from the pancre- 
aticoduodenal vein and from the femoral artery, and 
of lymph from the thoracic duct, as affected by 
stimulation of the great splanchnic nerve. 
By J. J. R. MACLEOD and R. G. PEAKCE. 
[From the Department of Physiology, Western Reserve University 
Cleveland, Ohio.] 
The distribution of diastatic ferment (glycogenase?) in the 
animal body would lead one to conclude that its site of production 
is in the pancreas. Thus : 
1. Extracts of this gland possess a glycogenolytic activity 
which is enormously greater than that of extracts of any other 
gland, or of blood serum. 
2. Blood serum contains the next largest amount of glyco- 
genase. 1 
These considerations prompted us to see whether blood from 
the pancreatico-duodenal vein is stronger in glycogenase than blood 
from the femoral or carotid arteries. They were found to be the 
same. We have recently repeated the observations with the modi- 
fication that some of the samples of blood were collected during 
1 Macleod & Pearce, Amer. Jour, of Physiology, 1910, xxv, p. 255; cf. also Wohl- 
gemuth and Benzur, Biochemische Zeitschrift, 1909, xci, p. 460. 
