8 
Scientific Proceedings (40). 
the skull, and pursuing its course centrally by means of the method 
of indirect Wallerian degeneration employed by van Gehuchten, 
we shall be enabled to locate anatomically the cardio-inhibitory 
center in the medulla oblongata. 
All that we feel justified in saying in the present preliminary 
communication, however, is that in the woodchuck one of the 
bundles into which the vagus nerve can be separated in the cer- 
vical region contains cardio-inhibitory fibers, while the others do 
not. This is unique, so far as we know, and may correspond on 
the efferent side to the case of the depressor nerve in the rabbit 
on the afferent side. 
5 (530) 
The relation "between bile -secretion and bile-pressure. 
By SUTHERLAND SIMPSON. 
[From the Department of Physiology and Biochemistry, Medical 
College, Cornell University, Ithaca, N. Y.] 
In the course of our work on the pressure of bile secretion in 
different animals, Herring and the author 1 found that in some 
cases the rate of bile flow was greater after the pressure was re- 
moved than it had been at the beginning of the experiment. The 
cystic duct having been clamped, a cannula was tied into the com- 
mon bile duct and connected by means of rubber tubing to a drop 
recorder which marked the rate of bile flow on a slowly moving 
drum. A vertical glass tube mounted on a millimeter scale was 
introduced by means of a T-piece between the bile duct and the 
drop-recorder, so that by closing the exit to the drop-recorder the 
pressure of the secretion could be observed in terms of a column 
of bile. 
In the course of some observations which I have since been 
making on bile pressure in the sheep, using the same method, I have 
observed on several occasions that after the bile had risen to its 
maximum height in the manometer, when the clamp was removed 
from the outflow tube the rate of flow was much greater than it 
had been before the pressure began to be recorded and that this 
increased rate of flow was maintained for a considerable time. 
^^Proceedings of the Royal Society, B, Vol. 79, 1907, p. 517. 
