130 
Scientific Proceedings (44). 
whether, as is the case with large primary tumors at this time, the 
growth will go on independently of the host's condition of nouris- 
ment. 
79 (604) 
Preliminary report upon the transmission of haemolysins from 
mother to offspring. 
By L. W. FAMULENER. 
[From the Research Laboratory, Department of Health, New 
York City.] 
In view of the fact that little work has been done upon the 
transmission of haemolysins from mother to offspring, and that 
there is a lack of agreement between the reported results of the 
workers in this field, the subject was taken up for further investi- 
gation. The question is of practical importance, since a parallel 
relationship exists between haemolysins and bacteriolytic bodies: 
the latter group of substances play a more or less important r61e 
in immunity against certain infections. 
Goats were selected as the most suitable experimental animals 
for these studies. In each case the animal was actively immunized 
by repeated injections of washed sheep-corpuscles given sub- 
cutaneously. Serum and milk samples were collected, throughout 
each experiment, and stored in an ice-box. All were tested at the 
same time, under uniform conditions, after the given experiment 
was closed. 
One series of animals were immunized immediately following 
the birth of their young. In all, excepting one case, the milk 
contained no demonstrable haemolysins. As evident, the sucklings 
from the mothers which supplied the negative milk, gave negative 
sera. The suckling which received the mother's milk containing 
haemolysins, showed no specific haemolysins at any time in its 
serum. The haemolysins did not appear (by test) in the milk in 
this case until about one week after birth of the young. 
A second series of animals were immunized at different periods 
during the course of gestation. Before birth of the young the 
animal's nipples were sealed to prevent the young getting any 
