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THOMPSON YATES LABORATORIES REPORT 
Morax 51 concluded that the bacillus was constantly present in muco-purulent 
catarrh. He described pure cultures of the bacillus and stated that inoculation of these 
cultures on his own conjunctiva produced acute inflammation. 
He also further describes the histological appearances of a piece of his con- 
junctiva which was snipped off. The bacilli in sections of this tissue were with 
difficulty demonstrated in the superficial layers of the conjunctiva ; in the deeper layers 
they could not be detected. 
Later, Juler mentioned that he had met the organism in many, but not in all, 
cases of acute ophthalmia. 
Morax and Beach" published a full account of their experiments with the 
bacillus which they cultivated on agar-agar with or without blood serum. 
Wilbrand, Saenger, and Staelin 44 describe an epidemic of conjunctivitis in 
Hamburg in which two varieties of micro-organism were found, one of which was 
Koch-Weeks bacillus. 
Juler, Panas, and Coppez 4 succeeded in observing the bacillus. Coppez 
draws attention to the often pseudo-membranous character of the inflammation to 
which I have already alluded. 
Gasparrini 15 mentions the occurrence of the bacillus in Italy. ■ 
Sidney Stephenson 40 & 41 gives a description of the outbreak and course of a 
small epidemic in the Central London District School, in which the characteristic small 
bacilli were found. He states that the presence of Koch-Weeks bacillus in the dis- 
charge is diagnostic of acute catarrhal ophthalmia, and is of the same opinion as 
Cuenod, 5 that the club-shaped organism described by other writers on the subject is 
pseudo-diphtheritic. 
He found the bacillus in three types of acute inflammation — 
1. Classical catarrhal ophthalmia. 
2. A form associated with large phlyctenule in and about the conjunctiva. 
3. A variety in which follicular enlargement is superadded, and also in a 
child suffering from chronic dacryocystitis. 
He succeeded in growing the organism on serum-agar, but states that after 
three to four days it dies, showing degeneration forms. 
Weichselbaum and Muller 47 (1898) published a very comprehensive work 
on the Koch-Weeks bacillus. They succeeded in isolating the bacillus in pure culture 
and establishing its etiological significance by successful inoculations on the human 
conjunctiva. 
Within the last year Dr. Reinhard Hoffmann 23 published an account of his 
cultural and inoculation experiments with this bacillus. He succeeded in growing it 
on swine serum-agar and 0*5 per cent, hydrocele fluid agar, but was able to sub- 
cultivate it only up to the fifth generation. He remarks that he obtained a growth 
on agar where a large amount of discharge was lying. The medium which gave him 
