272 
THOMPSON YATES LABORATORIES REPORT 
A second effect of injury may be to lead to new chemical change, and to new 
differences between the two solutions. Even if so, it is extremely probable that the 
localization of the resulting electrical phenomena to the region of the injury may be 
a consequence, not of the localization of the chemical change, but of the injury to 
the tubular membrane. 
In considering the physical structures of the nerve, therefore, the greatest stress 
is laid upon this separation of structures into 'internal' and 'external,' and upon 
the presence of the limiting surface which determines this separation. 
The experiments recorded in the subsequent sections of this paper have been 
devised to test the opinion that this is a matter of primary importance. 
