45 8 
THOMPSON YATES LABORATORIES REPORT 
Chart No. 3 gives a record of the temperature, pulse and respirations from 
December 1 6th to January 5th. It will be seen that the temperature was very similar 
in character to that recorded in charts 1 and 2, namely, periods of slight pyrexia, 
lasting three to four days, with intervals of four or five days in which the temperature 
remained below normal. The temperature charts shew an irregular but distinctly 
relapsing type of fever. 
From December 1 6 to December 1 8 the patient's temperature was raised, and 
on these days parasites were found in the blood, the greatest average number seen 
was fifteen under a three-quarter inch square coverglass. On December 19 the 
temperature fell below normal, and on this and for the next few days no parasites 
could be detected in the blood. 
Progress of the Case. The patient during the period in which I observed him 
was never confined to his bed, and was able to take short walks in the afternoons ; 
his appetite was distinctly good during the apyrexial periods, he did not complain 
again of pain over his spleen. On December 26 he was sent to the Cape for a 
change — a distance of seven miles from Bathurst, at the mouth of the river, where a 
good Government house facing the sea is built. Here I again had an opportunity to 
observe him, staying with him for two or three days. The fresh sea breezes appeared 
to produce some improvement. For the first few days he had a slight evening rise of 
temperature reaching to nearly ioo°, and trypanosomes again appeared in the blood 
but no further symptoms presented themselves. The day before I returned to 
Bathurst (December 30) I made the following note. 
' Mr. X slept longer than usual this morning, on getting up the puffiness about 
the eyes is very marked, especially the right lower lid which pits on pressure ; slight 
injection of the conjunctivae ; complains again of feeling week in the legs, the ankles 
are slightly oedematous ; no oedema anywhere else.' The blood was examined this day 
at 10 a.m., 12 and 4 p.m., no parasites were seen, the temperature on the previous 
night only rose tour points above normal. 
The patient remained five days longer at the Cape and then returned to Bathurst, 
temperature remained low. He seemed much improved, and was allowed to resume 
his duties. I made a blood examination on January 5, before he went up the 
river, a fresh preparation proved to be negative, one parasite was found in two 
smears ot blood. 
Case was treated with gradually increasing doses of arsenic and five grains of 
quinine daily. 
The chief clinical features of the case were as follows : 
1. General wasting and weakness, especially marked in the legs. 
2. Irregular relapsing fever, temperature never very high and lasting one 
to four days, with at times, morning remissions ; apyrexial periods of 
two to five days, when the temperature remained normal or 
sub-normal. 
