526 
THOMPSON YATES LABORATORIES REPORT 
leucopenia or scantiness of leucocytes in the end agonal stages of the disease, this 
seemed to be an indication for the worst prognosis. The leucopenia probably, 
mutually, explains itself, and the great abundance of leucocytes found, post-mortem, 
in the vessels of the internal organs. 
E. Cases of Illness at Instituto Lauro Sodre, and our own Infection 
Case A. Little boy had occasional attacks of fever ; these were stated to occur 
each month, according to the moon ; prophylactic quinine was given 
a few days before full (? new) moon ; no precise examination was 
made ; the child seemed somewhat anaemic, compared to his twin 
brother. 
Case 
I . 
Sept. 
I I . 
Febre de transpiracao o da acclimitasao. 
2. 
■>•> 
i5- 
Yellow fever. 
B. 
■>■> 
20. 
Quartan malaria. 
>> 
3- 
Oct. 
I . 
Febre amarella gastrica. 
?> 
4- 
•>■> 
17- 
? 
)) 
5- 
•>■> 
18. 
Febre amarella. 
•>■> 
6. 
>5 
28. 
Recurrent in bed several days. 
11 
7- 
About this time in next chalet to ours. 
On July 1 6 a man died of yellow fever ; he was an occupant of one of the 
chalets ; we were not able to obtain many details, so that the question whether he 
could have formed the original infecting case could not be determined. 
Case i. Robust middle-aged woman ; arrived from France, September I, 1900; 
came straight to Institute ; lives in room at stables, without any civilized con- 
veniences ; has not vised a mosquito net ; takes meals at chalet G. with the G.'s. 
Sept. 11. Quite well at 9 p.m. ; taken with some shivering about midnight ; vomited bilious 
matter, and severe headache. 
., 12. Severe, intense frontal headache ; no pain elsewhere ; facies, nil ; chest, nil; 
abdomen, nil ; tongue, flabby ; skin, moist, sweating, slightly ; temp., 38"7° ; 
pulse, 118. 4 p.m., headache still severe ; pain and tenderness at epigastrium ; 
pain in loins and calves ; face a little flushed, but no marked lacies or thoracic 
injection ; rather intense photophobia ; tongue, furred ; skin, hardly moist ; 
vomit, yellowish, with a good deal of mucus ; no ague parasites could be found in 
blood films ; temp., 37'6 Q ; pulse, 1 08. 
,, 13. Headache less ; skin moist ; no icterus ; no conjunctival injection ; no pain ; no vomit ; 
complains of weakness ; temp., 37 0 , pulse, 84. Evening, temp., 37 0 , pulse, 98. 
,, 14. Some headache; no icterus; tongue, slight fur, edges red; papillae swollen; 
tenderness and pain at epigastric angle ; no albumin (boil and nitric) ; temp., 
37° ; pulse, 98. 
,, 15. No icterus ; no fever ; no albumin ; gums rather swollen. 
