26 
with the dinical courses. These histological changes have 
been met in four cases prior to this year, that is in two 
monkeys and two wild cats. Dr. Rhein and I are studying 
this collection of cases very carefully and hope to make a 
separate report on them very soon. I have subjoined the 
cases found during the past year, together with notes of the 
observed clinical course and the pathological diagnosis 
made at autopsy. 
1736. Black Bear, ^, about 7 months old. 
Clinical Notes. — About August 19th, this animal was observed to hold 
his head in an unnatural position as if his neck was sprained. This was not 
verified by the observations of the Superintendent and Head Keeper, On 
August 25th he did not eat well. After some days of irregularity in eating, 
&c., he was found lying on his back and unable to get on his feet. This con- 
dition continued, with some improvement toward the end, until his death, 
September 12th. 
Pathological Diagnosis. — Acute enteritis, cloudy swelling of myocardium, 
chyle obstruction, ascites, acute pancreatitis, hydrothorax, hydro pericardium. 
Dr. Rhein' s Notes. — The pia of the spina) cord presented nothing abnormal, 
except that there were more nuclei when compared to the pia of the spinal 
cord of other wild animals. The blood vessels were numerous and distended 
and showed a slight increase of the nuclei of the walls. The cells of the anterior 
horns were somewhat diseased. Some were rounded; the nuclei in some were 
diseased or have disappeared; in some there was atrophy of the pigment, 
and some showed vacuolisation. There were, however, many more normally 
staining cells present. 
N euro-pathologic Diagnosis. — Poliomyelitis. 
1760. Weeper Cebus, c^, small. 
Clinical Notes. — This animal, ever since he was received, acted in such a 
peculiar manner, seeming to have only partial control of his movements, that 
he was known as the " Crazy Monkey." 
Pathological Diagnosis. — Chronic entero colitis, chronic adhesive pericarditis, 
early interstitial change in kidney. Edema of lungs. 
Dr. Rhein' s Notes. — The pia of the paracentral cortex was thickened and 
was the seat of a round cell infiltration of moderate degree, the cells being of 
the mono-nuclear type. The blood vessels of the cortex were congested and 
the nuclei of the walls were increased. The round cell infiltration of the pia 
had in some places extended into the cortical layers. 
The pia surrounding the medulla oblongata was also the seat of a slight 
round cell infiltration. The pia of the spinal cord, however, did not show 
any cellular infiltration. 
The cells of the anterior horns of the spinal cord were extensively diseased. 
The cells were swollen in places, some were surrounded by a glia proliferation 
and many of the cells showed marked vacuolisation, 
Neuropathologic Diagnosis. — Meningitis and poliomyelitis. 
1792. Green Monkey, $ , small. 
Clinical Notes. — Has been a cripple for a long time and finally was con- 
demned and killed at the laboratory. 
Pathological Diagnosis. — General lymphatic hyperplasia, chronic osteitis 
(Tibial). 
Dr. Rhein's Notes. — The pia in the paracentral region was the seat of a 
moderate round cell infiltration in some places. The blood vessels of the 
cortex were congested. The blood vessels of the pia were somewhat thickened. 
