27 
The cellular infiltration in the pia consisted mainly of cells of the connective- 
tissue type though some mono-nuclear cells were present. The pia of the 
medulla oblongata and spinal cord was also the seat of a round cell infiltration 
which was mainly around the posterior roots and was more marked in the 
lumbar region. The cells of the anterior horns in the cervical region were 
somewhat diseased. There was some vacuolisation and around the cells thus 
diseased was found an increase in the number of glia nuclei. Some of the cells 
were swollen, the nucleus displaced and around them the glia nuclei were in- 
creased. One cell appeared to contain some glia nuclei and was probably 
the seat of neurophagia. 
In the lumbar region the peri-cellular accumulation of the glia nuclei with 
neuronophagia was present. A number of the cells were diseased, showing 
atrophy of the pigment, swelling of the cell body and disappearance of the 
nucelus. There were present, however, many normally staining cells. The 
blood vessels of the anterior horns in the cervical region were congested, showed 
peri -vascular round cell infiltration and an increase in the number of the nuclei 
in the blood vessel wall. The pial indentations are also the seat of a moderate 
round cell infiltration which is fairly constant and general. In the limibar 
region the same condition is present but to a more marked degree. 
Neuropathologic Diagnosis. — Meningitis and poliomyelitis. 
1837. Burchell's Zebra, 9 , 9 years, 9 months old. 
Clinical Notes. — Ate well and appeared to be in good health until about 
seven hours previous to her death at which time she got down and after 
struggling for a short time lay quiet until she died. 
Pathological Diagnosis. — Constipation, acute parenchymatous nephritis^ 
cirrhosis of liver. 
Dr. Rhein's Notes. — The pia from the paracentral and other regions of 
the cortex of the brain showed a marked round cell infiltration which in places 
involved the superficial layers of the cortex. The vessels of the cortex were 
much congested and there was a marked peri-vascular round cell infiltration 
of the cortex. This round cell infiltration invaded in places the white mat- 
ter of the brain. In short there was an acute meningo-encephalitis. 
The spinal cord showed nothing abnormal except some slight round cell 
infiltration of the pia. 
Respectfully submitted, 
HERBERT FOX, M.D., 
Pathologist. 
