31 
these deeper parts. Arteries quite normal. Liver capsule and interstitial parts are on 
the whole normal. Perilobular fibrous tissue largely missing, but where remaining shows 
an overgiowth occurring in peculiar zonal arrangement and of old adult almost hyaline 
type. Its fibers are often arranged strikingly in whorls. Bile ducts, arteries, and veins 
quite normal. Parenchymal cells of normal size, finely granular, prominent normal 
nuclei and contain small quantities of granular golden brown pigment not nearly so abund- 
ant as commonly seen in severe anemias. Blood capillaries narrow and contain small 
quantities of red blood cells, and Kupfer's cells very frequently contain fine granules 
like those of parenchymal cells but of a greener tint. In a few isolated areas parenchymal 
cells are distinctly more swollen than others and many show disintegration of nucleus. 
Kidney capsule smooth, interstitial fibious tissue of organ proper highly fibrosed in peri- 
pheral parts but slightly in deeper. No lymphatic infiltrations or sclerosis of vessels 
anywhere. Tubular epithelium highly atrophic in subcapsular regions where, too, tubules 
are narrow. In deeper parts epithelium is at times so swollen as to occlude lumina, where 
it is coaisely granular and occasionally show some karyolysis. On the whole lumina 
are wide open rarely containing a pink hyaline or granular material. Tufts never show 
fibrosis. Bowman's capsule heavily thickened. Spleen shows slightly hyalinized capsule 
normal in thickness. General reticulum of pulp slightly fibrosed and poor in lymphocytes. 
Sinuses broad and crowded with red blood cells and small numbers of lymphocytes. Coarse 
granular blood pigment abundant showing greenish cast on focu.sing. Malpighian follicles 
normal in size, slightly fibrosed and in several instances a deposit of smooth pink material 
between its cells. Adrenal appears normal in all respects save for presence of a few small 
irregular areas of calcification in medulla. These appear apart from any recognizable 
necrotic or fibrous areas. In one place one appears to lie within lumen of blood vessel. 
No fibrosis or special congestion anywhere in organ and cells show normal details and 
normal numbers of vacuoles. Stomach shows normal muscular tunics. Submucosa thin, 
has densely arranged bundles of smooth pink character. Mucosa distinctly thinned 
shows comparatively few areas holding acid cells, consisting for most part of peptic type 
of gland. These are short and of broader calibre towards lumen than deeper, suggesting 
a hyperplasia of luminal portion. Stroma richly infiltrated with lymphocytes, not fibrosed 
or congested. Epithelium of crypts has rarefied appearance, shows no special degeneration. 
Bone marrow appears as widely separated large fat globules with intervening granular 
edematous material and no haemopoietic elements. Blood capillaries numerous and 
highly congested. Cord shows nothing abnormal in any part. 
4177. Rhesus Macaque, 180, Primary anemia, pleural 
and peritoneal adhesions, hyperplasia of bone marrow, 
acute catarrhal bronchitis, pigmentation of spleen, liver, 
and lymphnodes. 
3906. Rhesus Macaque, 156, Anemia, fatty degenera- 
tion of liver, chroic peritoneal adhesions, old rickets. 
3948. Ring-tailed Bassaris, Primary anemia, fatty in- 
filtration of liver, hemorrhages in intestine and spleen, 
hyperplastic bone marrow. 
Cretinism. 
Last year a report was made of the birth of some cretin 
wolves from a healthy mother. Another litter has been 
born to this female and a more complete history has 
become available, which, with a survey of the situation 
and the conclusions, are herewith appended. 
The material presented consists of the offsprings of a 
female gray wolf impregnated three times, by two different 
male wolves. On the first occasion she gave birth to two 
male cubs, which died within three days and were appar- 
ently normal ; they were probably not taken care of. The 
