74 
NAT. OUTER. ERICEiE. 
the calculus still remained." It does not appear from late experience, 
however, that any dependence is to be placed on this remedy in cal- 
culi of the bladder. In nephritic affections, from gravel, and other 
causes, we have abundant proof of its utility. 
Dr. Ferrias, whose testimony deserves the highest respect, says, 
u I have given this medicine in a considerable number of nephritic 
cases, in very moderate doses, and always with manifest advantage." 
He further observes, that he never found it necessary to give it in 
larger doses than five grains, and that in doses of a scruple or half a 
drachm he found it to produce nausea, even when given with opium. 
The same circumstance is mentioned by Lewis. "In all cases," 
says he, V that have come to my knowledge, it produced great sick- 
ness and uneasiness." 
In that variety of urinary disease which is accompanied with 
copious white sediment, especially in the last portions discharged, 
occasioning pain and irritation in the urethra, Dr. Prout states that 
" he has often seen the greatest advantage from the combined use of 
hyoscyamus and Uva ursi, together with the use of alterative pur- 
gatives." I have a patient under my care at this time, who has 
been for upwards of two years exceedingly afflicted with a pain in 
the region of the right kidney, attended with all the usual symptoms 
of renal calculus. He lias been gradually getting better under the 
continued use of Uva ursi, taken in doses of about twelve grains, 
three times a day, and is at present almost entirely free from any 
symptom of his disease. Professor Barton thought it particularly 
serviceable in nephritis depending on gout. " In my own nephritic 
paroxysm," he observes, " alternating with attacks of gout in the 
feet, I have certainly found the medicine of much service ; and I 
confidently and with much pleasure recommend it to the notice and 
trial of other sufferers from the same affection." 
Of the modus operandi of Uva ursi in nephritic and calculous 
disorders, we are entirely uninformed ; nor will we consume the 
reader's time by speculations upon a topic which has been so fruit- 
