2 I 2 
ON THE STOMACH C.l.ANDS Ol' THE RAT AND RABBIT 
be divided into two parts according to form and liistological structure, viz : 
the gastric cr\-pt andthe gland lumen. The epitheluim cells of the Gastric 
crypt arc, on the superficial epithelium, of elongated cylindrical form and firm- 
ly joined together, but they gradually become rounder and the contents in- 
crease towards the end part of the gland. The cells which enclose tho^ end 
part of the gland may be distinguished from those of the gastric crypt as the 
former are of very round form with the nucleus in the middle, while the 
contents are much clearer than those of the latter. When stained with h;emat- 
oxin the cells of the epithelium and of the gastric gland are more coloured than 
those of the end part of the gland. When eosin is used for staining the cells 
of the epithelium show some reaction, the chief cells of the cardiac gland give 
a v^ery good reaction. With mucous colour some reaction is obtained in the 
cells of the epithelum and in the chief cells of the fundus it is very good, 
while in the cells of the cardiac gland there is occasionally a very slight reac- 
tion but usually none at all. 
The result of the observations of colour reaction in the cells of the epithe- 
lium and in the chief cells of the fundus gland may be summarised as follows: 
with mucous colouring the cells of the cardiac gland and those of the fundus 
gland are affected in a quite opposite manner, and the cells of the epithelum 
of the fundus gland have a similar colour reaction to those of the cardiac 
gland. 
Among the intermediate cells between the gastric Crypt cells and the 
cells of the end part of the gland I have found Parietal cells. These, as Heiden- 
hein and other histologists have remarked, are of round or oval form with 
the nucleus in the middle, and the ends of those against the Lumen pointed. 
My finding Parietal cells among the intermediate cells agrees with the result 
of Heidenhein's observations (1870), when he found Parietal cells among the 
cylindrical cells of the gland outlet of the Fundus. Hentkowsky (1796) found 
Parietal cells in the outlet of the Pepsin gland and Oppel obtained a similar 
result in the case of a number of mammals. In the rat, however, the Parietal 
cells among the intermediate cells are very few and difficult to find, and 
