2^6 Dr. Clarke’s Obfervations on the 
not bear fo great a proportion to the females ; and that, there- 
fore, it is not to be expe&ed they fhould keep up their majority' 
fo long. But there is only a- Seventeenth fewer males pro- 
duced; whereas it has been already (hewn, that there is a much 
greater proportion between the deaths of Angle and twin males 
again ft the former and in favour of the latter. 
Such are the outlines, Sir, of my feptiments on this fub- 
je£t. I have affirmed the liberty of addrefling them to you 
without ceremony, as a well-wifher to every member of the 
republic of letters. I fhall be happy, fhould your fentiments 
happen to coincide with mine, or if I can be of any farther 
fervice in promoting your very laudable inquiries; 
I am. Sir, with great refpedt, &c. 
JOSEPH CLARK E. 
Lying- ra Hofpi ta!, . 
June 9, 1785. 
Dr. Clarkes fecond Letter to the Rev . Dr. Price. 
3 ^ Dublin, 0 < 5 t. 22, 17850 
ENCOURAGED by your approbation of my former let- 
ter, I will take the liberty of ftating to you a few more fads 
and obfervations, which I hope you will judge an Appendix to 
it of fome importance. 
With the view of afcertaining how far fome of the fore- 
going conjectures are well founded, and of determining with 
greater 
