THE 
INTRODUCTION^ 
I. T Am fcnfiblc that fomc may be apt to 
I think, it favours too much of Vanity 
and Prefumption, for any one, after 
fuch innumerable fruidefs Refearches of the 
ableft Chymifts, to attempt to find out a fafe 
Diflblvent of the Stone in the Bladder. The 
great Tendernefs of thofe Parts on the one 
hand, and the extream Hardneft of many of 
the Calculi on the other, do with too much 
Probability, make the cafe feem defperate. For 
after applying all imaginable chymieal Prepa- 
rations, it is found, that neither the alkaline, 
nor acid, the neutral, faline, fulphureous, nor 
faponaceous Menftruums, have any Effed on 
thefe Concretions ; Spirit of Nitre, which is 
too corrofive, being the only thing which has 
hitherto been found effedually to diffolvc 
them. Yet in a Matter of fo great Impor» 
tance, to the Eafe and Welfare of a confidc- 
rable Part of Mankind, we ought not wholly 
to 
