24 Proceedings of Royal Society of Edinhurgli. [sess. 
not stimulate the spleen to haemopoietic activity. The author con- 
firms this observation. He found that the spleen of a rabbit that 
had been copiously bled contained few erythroblasts, and nucleated 
red cells, and almost no giant cells. It is believed by some in- 
vestigators that in mammals, after embryonic life, the nucleus of 
the young red-blood cell becomes extruded, so that the corpuscle 
becomes non-nucleated, and as such enters the circulating blood. 
Omer van der Stricht is of this opinion; he believes that the 
extended nuclei are devoured by giant cells, and that the numerous 
nuclei in giant cells in blood-forming organs are such nuclei 
undergoing disintegration. The author is opposed to this view, 
because he has traced the development of the nuclei, but reserves 
his opinion regarding the significance of the remarkable increase 
in the number of multinucleated giant cells in the spleen when 
it is actively producing blood corpuscles in early life and after 
artificial anaemia. 
