332 Proceedings of Royal Society of Edinburgh. [sess. 
The quantity of the fluid was not limited. 
The diet agreed with the patient. The pulse and temperature 
remained normal throughout. For the first three days she was 
kept on the diet alone ; for the next five she had thyroid tabloids 
(Burroughs & Welcome’s) in increasing doses, and for the last two 
days of the experiment the thyroid extract was stopped. It had 
been intended to carry on the experiment a little longer, but the 
patient began to menstruate, which made it impossible. That men- 
struation has no disturbing influence on the metabolism has been 
shown by recent work done under von ISToorden’s direction. The 
patient was weighed periodically. All the nitrogen estimations 
were done by Kjeldahl’s method. The fasces were first mixed with 
dilute HgSO^, and dried at 100° C. 
Influeyice on Metabolism. 
Weight 
Nitrogen 
Urine. 
Faeces. 
Total 
Nitrogen 
excreted 
in grms. 
Date. 
in 
Kilos. 
of Food 
in grms. 
Quantity 
in c.cms. 
Sp. Gr. 
Nitrogen 
in grms. 
Weight 
(dried) 
in grms. 
Nitrogen 
in grms. 
11.10.94 
53-7 
16*00 
750 
1025 
11-277 
0 
0 
12. 
5 ? 
825 
1027 
12*284 
24 
2*194 
14*478 
13. 
? 3 
1220 
1021 
12*810 
15 
1*233 
13*043 
14. 
53*7 
3 3 
1736 
1015 
14*001 
33 
2*795 
16*796 
T¥ of a 
gland. 
15. 
3 3 
1900 
1017 
15*051 
23 
1*403 
16*454 
3 3 
16. 
3 3 
2200 
1013 
15*510 
26 
2*089 
17*589 
tV of a 
gland. 
17. 
1680 
1018 
Lost 
46 
3*135 
5 J 
18. 
51-4 
” 1 
i 1500 
1022 
15*490 
23 
1*132 
16*622 
1 gland. 
19. 
3 3 
1400 
1021 
16*100 
28 
1*799 
17*899 
20. 
51-0 
3 3 
1120 
1024 
15*800 
33 
1*841 
17*641 
During the experiment 16 grins, of nitrogen were taken per diem. 
Before the administration of thyroid 1*71 grms. were, on the 
average, daily excreted in the faeces. Thus 14*29 grins, were 
absorbed. During these two days an average of 12*5 grms. were 
excreted in the urine, leaving a daily gain of 1*79 grms. of nitrogen, 
or 11*2 grms. proteid, ^.e., 53*7 grms. of flesh. 
