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Proceedings of Royal Soeiety of Edinhurgh. [sess. 
On a Human Cyclops. By Alexander Bruce, M.D., 
F.K.C.P.E. (With Three Plates.) 
(Read March 2, 1891.) 
While the occurrence of the condition termed Cyclopia cannot be 
considered as altogether a rare event, the obscurity in which its 
pathology is still involved makes it desirable that a full description 
of every case should be put on record. The specimen in my 
possession was that of a well-formed female embryo which had 
apparently reached the seventh month. With the exception of 
the malformation to be specially considered, there was no abnor- 
mality either in its external appearances, or in the structure and 
disposition of any of its viscera. 
In the face the first point to attract attention was the remarkable 
lozenge-shaped single aperture in the middle line above the mouth, 
which was overhung by a small pendulous projection of skin 
attached to the forehead immediately above its centre. This pro- 
jection, which was evidently the only representative of the nose, 
was moveable, and presented the appearance shown in fig. 1, some- 
what like that of a miniature champagne bottle. It was attached 
by its narrow end and presented a slight dimple at its free 
extremity. One’s first impression on examining the median 
aperture was that it represented a single eye in the middle line, but 
a closer inspection revealed the fact that it was evidently formed 
by the fusion of the appendages of the two eyes, there being on 
either side a distinct upper and lower eye-lid provided with well- 
formed eye-lashes. The upper eyedids were closely fused in the 
middle line, but between the lower lids was a small fleshy projec- 
tion which was probably the representative of the caruncula 
lachrymalis. Above each upper eye-lid there was a distinct eye- 
brow. The floor of the cavity was somewhat irregular and lined 
by a highly vascular membrane, through which no indication of an 
eye could be detected. Below the median eye no indication of a 
nose was seen. The lips were well formed, except that the small 
