Sir Everard Home's Observations 
476 
case were depression of spirits, pain in the back of the head, 
and mania.* When in the ventricles, and also between the 
tunica arachnoides and pia mater, and between the dura and 
pia mater, melancholy, imbecility, apoplexy, and paralysis of 
one side, have been the accompanying symptoms, “f When in 
the ventricles, where there has been an unusual vascularity 
of the dura mater, violent affections of the praeconlia have oc- 
curred in the night during sleep, which have led to suicide. J 
When between the dura and pia mater in considerable quan- 
tity, a state of melancholy and imbecility of mind has been 
met with. § 
* Water in the third ventricle in sufficient quantity to separate and keep apart the 
thalami nervorum opticorum, also between the tunica arachnoides and pia mater, over 
the hemispheres, and under the tubercula quadrigemina, in an adult, were attended by 
pain in the back of the head, low spirits, and after drinking wine, very high spirits. 
This ended in mania, and, after three months, in death. 
f Twoounces in the lateral ventricles, one between the dura and pia mater ; the space 
between the tunica arachnoides and pia mater loaded with it, the consequences of 
attacks of inflammation upon the coverings of the brain in an adult were attended 
by these symptoms. The paralysis took place after the last apoplectic fit, and death 
ensued. 
J Two ounces in the lateral ventricles and a very unusually vascular state of the dura 
mater in an adult was followed by these effects. 
§ A gentleman fell from a horse. From that time he had head-aches, gradually be- 
came melancholy and imbecile. He lived three years in that stale. Four ounces of 
water were found between the dura and pia mater, on the right side. There was an 
exostosis ^th of an inch long from the parietal bone with a sharp point, in contact 
with that part of the dura mater under which the water lay. There were four ounces 
in the lateral ventricles, the posterior cornua were very small, there were also three 
ounces on the basis of the skull. 
