1888.] Dr A. Bruce on Absence of Corpus Callosum. 327 
minded, but could answer simple questions correctly, and could 
go messages. Could read and write. , Moderate oedema of lepto- 
meninges. I^o trace of corpus callosum. Lateral ventricles 
greatly dilated (this attributed to absence of corpus callosum). 
Commissure anterior and mollis present, also the fornix (its psal- 
terium absent). Brain weighed 1078 grammes. Two hemispheres 
were slightly asymmetrical. 
VI. Huppert, Arcliiv f. Heilkunde, heft. 3, p. 243, 1871, quoted 
by Knox. — An epileptic idiot, age 27. Brain weighed 1270 
grammes. Dura adherent to calvarium, which is symmetrical. Pia 
thickened, adherent to cortex. On removing falx 500 grammes of 
fluid escaped from the lateral and third ventricles, which were found 
greatly dilated. Corpus callosum and its radiating fibres absent. 
Third ventricle covered by a thin membrane. Septum lucidum 
apparently absent (perhaps some trace left in a lateral band of white 
matter). Fornix (anterior and posterior pillars) present (body and 
commissure absent). Other commissures present, the middle en- 
larged. Mental condition, entire absence of attention, memory, or 
judgment. Began at age of four to walk and to speak indistinctly. 
Never could read or write. 
VII. Malinverni, Giornal. del. R. Acad, di Torino, 1874; also 
Gazette Med. de Paris, January 16, 1875 ; see Knox, l.c. — Soldier, 
aged 40; of ordinary intelligence, but with a slight tendency to 
melancholia and taciturnity, and untidiness in his habits. Brain 
shows absence of corpus callosum, septum lucidum, and gyrus for- 
nicatus. (The latter two statements must be received with caution.) 
VIII. Knox, Glasgow Med. Jour., April 1, 1875, p. 227. — 
Female, aged 40 ; extremely idiotic, muscular system well developed. 
(For further details see original article.) Head of normal size, forehead 
low, occiput flat, brain 36J ounces; hemispheres nearly symmetrical. 
Posterior horns of ventricles dilated, ependyma thickened (fig. 2). 
“ The corpus callosum appeared to be wholly awanting, or only repre- 
sented by a very slight ridge {rh), which anteriorly was scarcely 
perceptible, but posteriorly was about j^th of an inch in depth. It 
began in front above the lamina cinerea, and passed upwards and 
backwards attached to the side of the general cavity of the ventricle, 
forming the upper border of a layer of white matter, the lower border 
of which was part of the fornix. About halfway back it became 
