483 
1907-8.] On the Effects on Metabolism of Chloroform. 
The results of these experiments may be tabulated : — 
Table XVI. 
Urea Nitrogen. 
Bohland’s. 
Morner’s. 
Exp. 
Before. 
After. 
Per cent. 
Rise. 
Before. 
After. 
Per cent. 
Rise. 
1 
! 84 85 
88 87 
4 
78 81 
84 83 
6 
2 
... 
78 
86 
10 
3 
78 75 
86 86 
io 
74 73-5 
86 87 
10 
4 
83-5 
84 82 
0 
83 
84 80-5 
0 
5 
88 87 
90 90 
3 
87 87 
90 89 
3 
6 I 
1 
83 
85 81 
•01 
The effect of the administration of chloroform to the extent to maintain 
full anaesthesia for periods of from one to three hours in the dog is 
generally, although not always, to cause a rise in the proportion of nitrogen 
in the form of urea. 
4. Ammonia Nitrogen. — In Experiments I., II., and III., there was a 
distinct fall in the proportion of nitrogen in ammonia ; in IV. and VI., where 
the rise in urea nitrogen was absent, there was no change. In V. it was 
not determined. 
5. Creatinin Nitrogen. — In the one experiment in which this was 
investigated (Experiment VI.) there was unfortunately no change in the 
distribution of the “ urea ” nitrogen. No very marked change in the amount 
of creatinin nitrogen could be determined, but it roughly follows the 
excretion of total nitrogen. There is no distinct fall in the proportion of 
creatinin nitrogen. 
6. The Turin and Uric Acid Nitrogen were not investigated in 
this series. 
7. The Nitrogen not in Urea and Ammonia showed a fall in 
Experiments I., II., and III., the experiments in which the urea nitrogen rose, 
and no marked change in IV. and VI. 
8. Sulphur. — This was determined only in Experiments V. and VI., 
where the disturbance in the proportion of urea nitrogen was trivial or 
absent. The total sulphur ran fairly parallel with the total nitrogen, although 
the usual divergences were manifest. 
The Oxidised Sulphur , both as regards total amount and its proportion 
to the total sulphur, showed no variation ascribable to the influence of 
