484 
Proceedings of the Royal Society of Edinburgh. [Sess. 
chloroform. A curious tendency for a day of low proportionate excretion 
to be followed or preceded by a day of high excretion was observed. 
In these experiments protein was present in the urine once (Experi- 
ment II.) in appreciable amount, and twice (Experiments III. and IV.) in mere 
traces. In Experiment II. there was a deposit of fatty cells resembling 
those of the kidney, but not forming tube-casts ; and a few similar cells 
were present in Experiment III. 
No reduction of Fehling’s solution was obtained except in Experiment III., 
when a very slight reduction was noted on the day after the administration 
of chloroform. The reduction was so slight that no attempt was made to 
determine if it was due to sugar. 
In Experiment V. the administration of ether for two hours, although it 
was followed by a slight albuminuria, caused no marked change in the 
protein metabolism. 
Series II. — Chloroform by the Stomach. 
In the next two experiments 20 to 25 c.c. of chloroform dissolved in 
100 c.c. of olive oil were administered by the stomach-tube, and as sickness 
was to be expected, food was withheld on the day of administration, some- 
times entirely, sometimes merely till late in the evening. The dog was on 
both occasions somewhat excited, but showed no signs of anaesthesia. 
Experiment VII. — Setter Bitch. Weight, 18 kilos. 
Table XVII. 
Day. 
Urine in 
c.c. 
Sp. G. 
Total 
Nitrogen. 
Urea 
Nitrogen. 
M. & S. 
Uric Acid 
Nitrogen. 
Creatinin 
Nitrogen. 
nh 3 
Nitrogen. 
1 
570 
1016 
j 5-99 
5-28 
0-079 
j 0T28 
2 
910 
1014 
\ 5*91 
5-28 
0-091 
0-124 
} 0T28 
*3 
410 
1016 
3-42 
2-83 
0-049 
0-079 
0T23 
+4 
360 
1036 
6-42 
5-28 
0-018 
0126 
0-44 
5 
945 
1018 
12-56 
10*24 
0-189 
0-236 
0-96 
6 
675 
1016 
6-01 
4-46 
0135 
0-145 
0-527 
7 
360 
1019 
4-54 
3-50 
0-032 
0-149 
0-316 
8 
830 
1014 
6-31 
5-20 
0-074 
0T50 
0-594 
9 
360 
1013 
3'29 
2-70 
0-050 
0-044 
0-134 
10 
780 
1012 
5-38 
4-54 
0-085 
0-079 
0-260 
11 
560 
1017 
5-29 
4-40 
12 
920 
1014 
Dog weighed 15 kilos. 
On third day dog fasted, and 20 c.c. chloroform in 75 c.c. olive oil given. 
Dog vomited.* 
