335 
1910-11.] A Study of Artificial Pyrexia. 
0'13 grm. gave a rise of temperature which began in half an hour, and 
reached a maximum of 40 '3° C. in one and a half hours. On a second 
trial with the same dose on the same rabbit, the rise came in half an hour 
as before, but the maximum did not come until two and three-quarter hours 
and was 39‘4° C. (Charts I. and II.). 
For the effect on dogs, see p. 339. 
It was next necessary to follow the course of the loss of heat under 
ether, and its effect upon the temperature. 
The following results were obtained in two experiments with the anaes- 
thetic. In each the temperature fell in a curve similar to that of a mass 
cooling by radiation and conduction unaffected by physiological action. The 
rate of cooling was at first 3° in the hour (Charts III. and IV.). 
