62 Proceedings of Royal Society of Edinburgh. [sess. 
amount excreted upon the left side, no quantitative analysis having 
been made, it certainly was present in larger quantity than upon * 
the right. These results may be explained as corresponding to the 
results gained previously and already noted. 
Chloroform . — As was to be expected when this anaesthetic was 
exhibited (Expt. Y.), the reducing substance manifested itself in 
abundance upon both the injured and also the uninjured sides. 
Ether and Chlofoform . — In the instance in which these two 
anaesthetics were combined, a very interesting result was gained 
(Expt. YI. and VII.). 
If the chloroform was given to any pronounced extent both sides 
showed the reducing substance, but in those instances wdiere the 
chloroform was only given at the earliest stages, and its administra- 
tion stopped before the commencement of the collection of the urine 
for analysis, a different condition appeared to be induced. 
Under these circumstances no reducing substance was present in 
the urine secreted by the normal and uninjured kidney, but in the 
urine which flowed from the other kidney, the nerves of which had 
been previously divided, this reducing substance was readily demon- 
strated. 
In the case of Experiment VI. it was found on the left side only, 
but there only in small quantity, and limited apparently to only a 
short period of time (YI., L. 2), for none could be detected, not even 
a trace, in the first or last stage of the observation. No traces 
could at any time be obtained on the right side at any stage. 
In Experiment VII., however, a further point is illustrated. This 
substance appeared distinctly throughout the whole period of observ- 
ation in the left secretion, i.e ., the side upon which section had been 
performed — but much more markedly during the second period 
(VII. L. 2), during which it seemed to reach its maximum and to be 
present in quantity, and then again to fall off. There was no trace 
detected on the right side. 
In these instances, therefore, it was found that this reducing sub- 
stance appeared upon the left side only, — upon the side where 
complete division of the renal nerves had been effected,— and also that 
the greatest output, in the former instance (YI.) the only output, 
was found to correspond with the period of the greatest activity of 
the renal epithelium, if the eliminative activity may be judged of 
