RAYLESS GOLDEXROD AS A POISONOUS PLANT 13 
July 14 and 1G. His condition remained about the same during 
these days. Xo trembling was noted, although the animal was stupid 
and inactive. 
July 17. While being weighed in the morning, he commenced to 
tremble violently. The trembling was so severe that he was unable 
to stand upon his feet. These spells of trembling were repeated 
several times. Figure 8 shows this animal at 9.48 a. m. 
July 18. "When observed during the forenoon he exhibited periods 
of trembling and extreme weakness as on the" preceding day.-. 
July 19. The condition of the animal remained the same with no 
marked symptoms except the trembling and weakness. 
July 21. At 8.45 a. m. the animal was very quiet and stupid, 
standing in a humped-up position. When observed in the after- 
noon at 4.3s p. m. he was trembling and was unable to remain upon 
his feet more than two or three minutes at a time. 
July 22. At 6.45 a. m. he was found lying stretched out on the 
right side. He was raised to his feet and stood for a few seconds 
and then began to tremble. The trembling grew very violent and 
he lay down, falling on his right side. After a few deep breaths 
he died, at 6.49 a. m. 
This animal was made sick in 17 days of feeding, receiving in thac 
time 22.82 pounds, and. after the first symptoms appeared, ate 8.47 
pounds of Aplopappus. An autopsy was made immediately after 
death! Regular observations of temperature, pulse, and respiration 
had been made, but nothing abnormal was noticed in these particu- 
lars except a high rate of respiration at 4.38 p. m.. July 21, when he 
was breathing 132 times a minute. The only marked symptoms in 
the course of the illness were the weakness, stupidity, and trembling. 
DISCUSSION AND GENERAL CONCLUSIONS 
SYMPTOMS 
Depression and weakness. — The first effect noticed in poisoned 
animals is marked depression. The animals are inactive, appear 
stupid sometimes, particularly in the cases of the sheep, stand 
** humped up." and move with a more or less stiff gait. The 
u humped-up " position is shown in the picture of steer Xo. 851, 
Figure 4. The stiffness and weakness are more pronounced in the 
forelegs. In cattle Xos. 892 and 840 this was shown very clearly, 
for when somewhat wearied by exercise they would come down on 
their knees and sometimes even attempt to move along in this posi- 
tion. A picture of sheep Xo. 589 in this position is shown in Figure 
8. This inactivity gradually increase.- and culminates in extreme 
weakness, the animals in the later stages lying down most of the 
time, and eventually, in the more serious cases, being unable to rise. 
Figure 7 show.- that condition of weakness in sheep Xo. 373: Figure 
6 shows a more advanced case in steer Xo. 851; and Figures 1» and 1<> 
show cow Xo. 808 in the last stages. 
Constipation. — Constipation is present in most cases, but may be 
preceded or followed by a period of diarrhea. In the later stages 
the feces are not only hard but bloody. 
Urine. — The urine is generally very light in color, and the animals, 
when exercised, frequently have an almost continuous dribbling of 
the urine 
