22 BULLETIN 125, U. S. DEPARTMENT OP AGRICULTURE. 
membranes of the mouth somewhat cyanotic, and the ears drooped. At 1.47 p. m. 
she was given subcutaneously 8 grams of caffein. At 1.49 p. m. she threw her head 
up and held her breath for about a quarter of a minute. She repeated this action 
several times. At 2.03 p. m., her temperature was 100° F. The animal seemed 
somewhat stronger. Her respiration was still variable, running as high as 180 per 
minute. Her pulse was about 80. She was still frothing at the mouth and appeared 
to be in pain. At 2.20 p. m. she had a hard time to breathe. She shook her head, 
staggered about, and lay down. Her respiration was slow and labored. At 2.22 p. m. 
her respiration w.as getting more rapid. At 2.23 p. m. the animal seemed to be in 
great pain; her breathing nearly stopped for a minute, but started again in a panting 
manner. Her respiration continued irregular, first fast and then slow and labored. 
At 3 p. m. her temperature was 100.2° F. and her respiration 84, but not as labored 
as at 2.03 p. m. She was still frothing at the mouth. Her pulse was 96 and strong. 
At 3.30 p. m. her respiration was 160. She fell upon her knees, struggled to get on 
her feet again, but finally lay down. At 4.15 p. m. she was groaning more or less and 
staggered as she attempted to walk. Her respiration was 90. At 4.30 p. m. she was 
lying down and her respiration was very nearly normal . Her temperature was 99 . 1 ° F . 
At 5 p. m. she was down again and in pain, groaning continuously, her respiration 
slower than for some time previous, the rate being about 60 per minute . At 5 .04 p . m. 
the animal was lying sprawled out upon her belly. Her respiration was 168. At 
5.38 p. m. she appeared very stupid, almost as if sleepy. She was given subcutane- 
ously 6 grains of caffein sodiobenzoate. At 5.45 p. m. her temperature was 99.4° F., her 
respiration 120 and very variable, and her pulse 96. At 7.10 p. m. her temperature 
was 99.7° F. Her respiration was slow and variable. After expiration there would be 
a pause followed by two short and shallow inspirations close together. These would 
be followed by a long inspiration, then a full expiration accompanied by a groan. 
This was repeated over and over again, the whole cycle taking about 20 seconds. The 
animal on the whole seemed to be brighter than at 6 p. m. 
At 8 p. m. the animal was given 5 grains of caffein sodiobenzoate. Her temperature 
was 100.8° F., respiration 10, and pulse 120. At 10 p. m. her temperature was 100.2° 
F., pulse 120, and respiration 4. The inspiration was deep and the expiration was 
accompanied by a groan. At 10.55 p. m. her temperature was 100° F. At 11.15 p. m. 
her respiration was 18 and pulse 108. Her general condition was unchanged. 
On July 20, at 7 a. m., the animal's pulse was 100, temperature 100.8° F., and respi- 
ration 11. She was then lying with her head bent under her body and would probably 
have died in that position had she not been relieved. She seemed at this time uncon- 
scious. At 8.45 a. m. her temperature was 100.6° F, pulse 84, and respiration 12. At 
10 a. m. her respiration was 10, and her pulse 84. The animal was in a comatose con- 
dition. At' 10.50 a. m. her respiration seemed to be getting more shallow. At 11.15 
a. m. she seemed somewhat brighter than earlier in the day. At 12 m. her temperature 
was 102.6° F., respiration 12, and pulse 108. During the afternoon she had been lying 
in practically the same position, with her head slightly raised, resting upon a support. 
She was too weak to move herself at all. At 3 p. m. her respiration was 12. At 3.30 
she was given subcutaneously 10 c. c. of whisky. At 4.20 p. m. her temperature was 
102.8° F., respiration 36, and pulse 116. At 8.05 p. m. she was given subcutaneously 
5 c. c. of whisky. At 9.30 p. m. her temperature was 104.6° F., respiration 18, and 
pulse 120. 
On July 21, at 5.45 a. m., she was found in practically the same condition as the 
preceding night. At 6.45 a. m. her temperature was 104° F., respiration 24, and pulse 
148, and weak. At 9.50 a. m. she was given subcutaneously 5 drops of fluid extract of 
digitalis in 8 c. c. of whisky. At 10.15 a. m. her pulse was somewhat stronger than 
before the digitalis was given. At 11 a. m. her pulse was 102, temperature 104.6° F., 
and respiration 48. At 11.15 a. m. her respiration was fairly deep, but was somewhat 
