6 
BULLETIX 942,, IT. S. DEPARTMENT OF AGRICULTURE. 
they exhibited violent spasms, accompanied with running move- 
ments. The temperature in the two fatal cases, Sheep 519 and 547, 
ran for a period very high, reaching a maximum of 107° F. in Sheep 
519 and 109.6° F. in Sheep 517. In the spasms the latter animal 
threw itself at times in the opisthotonic position, and occasionally 
drew its head toward the thorax with a spasmodic motion. 
In comparing these symptoms with those shown by Asclepias 
galioides there is nearly a complete resemblance. The symptoms 
exhibited in the fatal case of one could not be distinguished from 
those seen in the other. In the cases of intoxication with recovery, 
no spasms appeared, and in this respect A. pumila differs from A. 
galioides. This, however, may be explained by the fact that A. 
pumila is much less toxic than A, galioides, and it may be supposed 
that in the cases of intoxication there was not enough of the poi- 
sonous principle to produce the spasmodic stage. 
TIME EEQUIEED TO PKODUCE SYMPTOMS. 
The following table shows the time that elapsed after the feeding 
of A. pumila before symptoms appeared: 
Table 2. — Time elapsed after feeding A. pumila before appearance of symptoms. 
Quantity 
Time 
Quantity 
Time 
fed 
elapsed 
before 
fed 
elapsed 
before 
Animal. 
per 100 
Besult. 
Animal. 
per 100 
Result, 
pounds of 
symptoms 
pounds of 
symptoms 
animal. 
appeared. 
animal. 
appeared. 
Pounds. 
Hrs. Mins. 
Pounds. 
Hrs. Mins. 
Sheep 546. . 
0.787 
Sick 
13 40 
Sheep 546... 
1.339 
Sick 
13 40 
Sheep 482.. 
.787 
...do 
30 15 
Sheep 512... 
1.496 
...do 
13 10 
Sheep 486.. 
.827 
...do 
12 37 
Sheep 520... 
1.693 
...do 
13 46 
Sheep 536.. 
.866 
...do 
16 50 
Sheep 539... 
0.787 
...do 
15 50 
Sheep 539.. 
.905 
...do 
16 — 
Sheep 516... 
1.85 
...do 
17 40 
Sheep 552. . 
.984 
...do 
15 45 
Sheep 542... 
1.968 
...do 
13 8 
Sheep 516.. 
.984 
...do 
21 — 
Sheep 519. .. 
2.165 
Died 
20 20 
Sheep 547.. 
1.063 
...do 
13 8 
Sheep 5 J 7... 
2.559 
...do 
15 50 
Sheep 554. . 
1.181 
...do 
14 13 
The average time of all cases shown in the table was 16 hours 17 
minutes. 
CONTINUATION OF SYMPTOMS. 
It was noticed in the experimental cases of poisoning with A. 
pumila that the symptoms in some cases continued for a long period 
of time. The following table shows these facts. This table was 
prepared by taking the time between the appearance of symptoms 
and the last time when symptoms were noted. The actual periods 
were probably somewhat greater than those in the table, for in most 
cases the first symptoms were noted in the morning, and the animals 
may have been sick earlier. It is probable, too, that the symptoms 
extended somewhat beyond the time the table would indicate. 
