OSSIFYING CARTILAGE. 
173 
*0 c ' 
’IPS 
Vfc d 'B 
6 gVo §■ 
8 5 i 
81 % ‘iM I 
? 8 ” |« 
4 pa c- c-c. ° 
0 o Bo ° « ° e '’, 
° ° °<S> CP 
° ^8 0 <gP 
fig. 135. will be found, that at the 
proximal extremity b, in 
which the formation of bone 
is going on, the cartilage- 
cells are arranged in linear 
series, but that at the distal 
one, A, only a trace of such 
arrangement is visible. 
The ultimate osseous gra- 
nules were first pointed out 
by Mr. Tomes, they cannot 
be well seen in very com- 
pact bone until it has been 
boiled, but may be readily 
distinguished in imperfectly 
developed bones. In a ver- 
tical section of a portion of 
the os fronds, belonging to 
the Histological Collection, a 
spot of imperfectly formed bone occurs near the centre, 
in which the granules are very visible. In certain forms 
of ossifie deposit, as in the early stage of ossification of 
the coats of arteries, nothing but granules can be seen, 
and the same holds good in ossified fibrous tumours 
and cysts found occasionally in various parts of the 
body. 
The ossifie granules are generally discoverable in the 
pus which escapes from a necrosed bone. If a specimen 
Vertical section of one of the 
phalanges from the fore-foot of a 
Pig : a, distal extremity ossifica- 
tion going on slowly, b, proxi- 
mal extremity, ossification pro- 
ceeding rapidly. 
