196 
HISTOLOGY OF ANIMALS. 
pieces, in all parts of the field of view. A specimen of 
this kind from the Eel is represented in Fig. 148, e; 
the same thing is very common in other fishes, especially 
the Lamprey and Lancelet. 
Before fatty degeneration commences in voluntary 
muscle, the transverse striae disappear ; and I have long 
known that the first trace of this disease is marked by a 
disturbance of the particles of myoline, which appear 
as so many very minute granules scattered irregularly 
within the sarcolemma, leading one to suppose that 
the delicate cell around each particle had given way, 
thereby allowing the myoline to escape, and destroying 
all regularity both of the transverse and longitudinal 
markings. As the disease progresses, the myoline is 
replaced by minute, highly-refracting globules of oil, 
until at last the whole sheath is full of them. 
In a specimen of this diseased condition of mus» 
FIG. 149 . 
Rip 
ittH 
a, fasciculus of voluntary 
muscle full of oil globules. 
b, fasciculus of voluntary 
muscle exhibiting a disturb- 
ance of the particles of myo- 
line. 
cle from the human subject, 
Fig. 149, B, the transverse 
striae are visible in the upper 
part, and a partial disturbance of 
the myoline in the lower ; in 
another preparation (Fig. 149, a) 
the disease has so far advanced 
that all trace of striae is com- 
pletely lost, and globules of oil, 
in this case of nearly equal size, 
but in others of variable diameter, 
occupy the sarcolemma. The 
