THE WHOKLED MILKWEED AS A POISONOUS PLANT. 
35 
creased susceptibility, and accumulation. Following is a tabulation 
of repeated feedings : 
Table 4. — List of repeated feedings and results. 
Animal. 
Steer 750.. 
Horse 126. . 
Sheep 478.. 
Sheep 506.. 
Sheep 509.. 
Sheep 470.. 
Sheep 470.. 
Sheep 470.. 
Sheep 470.. 
Date of 
feeding. 
1918. 
Aug. 22 
Aug. 25 
Aug. 26 
Sept. 22 
July 30 
Sept. 20 
June 19 
Aug. 19 
Aug. 28 
Aug. 29 
Sept. 2 
Sept. 5 
Aug. 26 
Sept. 11 
Sept. 12 
Sept. i6 
Sept. 18 
Sept. 20 
June 20 
June 21 
June 22 
"July 2 
July 3 
July 4 
July 5 
Quantity fed 
per 100 pounds 
Result. 
of animal. 
Pound. 
0.22 
Not sick. 
.626 
Do. 
.845 
Very sick. 
.551 
Death. 
.22 
Very sick. 
.140 
Not sick. 
.165 
Do. 
.110 
Do. 
.138 
Do. 
.138 
Do. 
.147 
Do. 
.167 
Sick. 
.132 
Not sick. 
.148 
Symptoms. 
Not sick. 
.151 
.160 
Do. 
.172 
Do. 
.184 
Death. 
.189 
Not sick. 
.22(ate0.2) 
Do. 
.22(ate0.24) 
Death. 
.0473 
Not sick. 
.0473 
Do. 
.0558 
Do. 
.055 
Do. 
Animal. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 470. 
Sheep 522. 
Sheep 522. 
Sheep 522 . 
Sheep 522 . 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Sheep 522. 
Date of 
feeding. 
10 
1918. 
July 
July 
July 
July 
July 
July 11 
July 12 
July 13 
July 14 
1919. 
Aug. 11 
Aug 14 
Aug. 16 
Aug. 18 
Aug. 20 
Aug. 23 
Aug. 25 
Aug. 27 
Aug. 29 
Sept. 1 
Sept. 6 
Sept. 9 
Sept. 11 
Sept. 22 
Quantity fed 
per 100 pounds 
of animal 
Pound. 
0.0473 
.0473 
.0473 
.05 
.05 
.05 
.05 
.05 
.05 
142 
155 
162 
,176 
,183 
,191 
,198 
,204 
,219 
,247 
275 
198 
147 
Result. 
Not sick. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Do. 
Symptoms 
Sick. 
Sheep 470, from July 2 to July 14, was fed a daily ration of from 
0.05 to 0.0558 pound, receiving in the whole period a total of 0.6473 
pound, with no resulting ill effects. 
So far as cumulative effect is concerned, the 5 sheep and Steer 750 
are the only animals that would have any bearing on the question. 
Sheep 470 received in 15 days about four times the toxic dose with 
no effect. Sheep 478, in addition to the feedings of June 19 and 
August 19, received on August 28 and 29 and September i doses 
equal to that which proved fatal for No. 483, yet on September 5 it 
was poisoned by an average dose, which was practically like that 
given on June 19 with no result. 
In the case of Sheep 506, which on September 11 showed symptoms 
from 0.148 pound, slightly increased doses on September 12, 16, and 
18 produced no results, and death was caused on September 20 by 
0.184 pound. 
Sheep 509, which was not affected by 0.2 pound on June 21, was 
killed the next day by 0.24 pound, which is probably close to the 
toxic or lethal dose for the plant as eaten by a sheep. 
Sheep 522, besides having received three feedings of marc, was 
given 14 feedings between August 11 and September 22 of quantities 
varying from 0.142 pound to 0.275 pound. All the feedings except 
the last were of material from Palisades, Colo., which, as shown else- 
where (p. 37), was less toxic than that from other localities. On 
September 22 it was made sick by 0.147 pound of leaves from Rock- 
ville, Utah. 
