20 BULLETIN 1012, U. S. DEPARTMENT OF AGRICULTURE. 
TYPICAL CASE OF SHEEP 588, 
In most of the cases the symptoms were neither very acute nor 
very prolonged. Sheep 588 may be considered fairly typical of one 
of the more pronounced cases. This sheep was a yearling wether 
weighing 101.25 pounds at the time of the experiment. It was 
taken into the corrals for observation on the morning of July 17, 
1920. The experimental feeding was commenced July 19, 1920. 
On account of the large quantity necessary to produce toxic effect, 
the plant was administered in several doses. At 10.57 a. m. 200 
grams.of stems, leaves, and flowers of the plant were given. The 
sheep was somewhat salivated as the result of this feeding, but no 
further symptoms developed during the administration of the plant. 
Other feedings were made at 11.15 a. m., 11,37 a. m., 11.51 a.m., 
41.57 a.m-:, 12.06 p.m., 12:22. pm., 1.10 p-m- vand 1. 20 p.m. Nene 
feedings scams Ine from 100 to 200. grams were given. The 
feeding in each case occupied about five minutes. All told, the 
animal received an equivalent of 2.939 pounds of green plants to 100 
pounds of animal. 
No symptoms were noted until 4.24 p.m. At that time the sheep 
was regurgitating and frothing at the mouth. The temperature was — 
102.8° F., pulse 100, respiration 72. At 5.30 p. m. the animal was 
still badly salivated, and was standing with the hind legs braced 
back and head held rather high. The respiration was fast and deep. 
At 5.55 p. m. the animal showed unsteadiness when attempting to 
walk. There was at this time distinct hyperesthesia; it was startled 
by sudden noises or by being touched. The condition remained 
the same during the evening. Observations continued until 10.30 
p.m. The salivation continued and the animal was unsteady on its 
feet, and occasionally, when startled, would fall down but was able to 
get uponitsfeetagain. At9.45p.m.and 10.30 p.m.it was found lying 
down but got up readily, although its gait when walking was very 
unsteady. 
On July 20, at 7.10 a. m., when observed it was still salivated, 
was quiet and depressed, but much stronger than the night before. 
‘During the day the condition of the animal improved gradually and 
on the. morning of July 21 it was turned into the pasture, as it seemed 
to have eed completely. 
DISCUSSION AND RESULTS. 
SYMPTOMS. _ 
Salivateon.—Salivation occurred in all but 2 of the cases. There 
was evidence of nausea in 6 cases. In some of these cases this was 
shown by more or less regurgitation. Actual vomiting occurred in 
5 animals. 7 
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