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almost double tbe height when the man was on nitrogenous food. This 
feebleness of expansion shown by the sphygmograph was quite in accord- 
ance with the impression given to the finger. The softness of the pulse 
proved it was not owing to increased resistance of the arterial wall. With 
regard to the temperature, the means are so close to those of the days on 
ordinary diet, that having regard to the fact that the period was shorter and 
therefore more liable to error, and that some observations were omitted on 
the marching-day, it may be concluded that a non -nitrogenous diet con- 
tinued for five days neither raised nor lowered the temperature of the axilla 
and rectum. It therefore shows that when the nitrogenous food of a 
healthy man was reduced to one-half for five days, and he was kept for five 
days more without nitrogen, he was able on the fourth day after such de- 
privation to do a very hard day’s work. The non-nitrogenous diet, consist- 
ing of butter, oil, starch, and sugar, kept him perfectly well; all functions 
seemed natural, the temperature of the body was unaltered, the pulse be- 
came very soft, and the sphygmographic tracings showed very feeble mark- 
ings ; but it was not materially altered in frequency. The circulation 
appeared to be properly carried on, as far as could be judged of by the 
man’s own feelings. The health, as judged of by the man’s feelings and 
the absence of objective signs, was perfect. On account, however, of the 
feebleness of the heart’s action, it was not thought right to continue the 
experiments, which had, he believes, sufficiently proved that force necessary 
for great muscular work can be obtained by the muscles from fat and starch, 
though changes in the nitrogenous constituents of the muscles also go on, 
which have as one effect an increased though not excessive elimination of 
nitrogen after the cessation of the work. 
j Bromide of Potassium in Poisoning by Strychnine . — Dr. Herbert contri- 
butes a paper on this subject to the “ New York Medical Journal ” (March). 
He gave it in a case of poisoning by strychnia as a dernier ressort, in doses 
of ninety grains or more, every half hour. “ In twenty minutes after the 
administration of the first dose there was perceptible improvement, which 
continued. In two hours the patient could move his arms. The bromide was 
then given at the rate of one drachm every hour ; but, the convulsions coming 
on again with greater severity, the remedy was given for one hour every 
fifteen minutes. At the end of that time he felt easier again, and the bromide 
was continued in smaller doses, at intervals of a half-hour to two hours, 
according to circumstances, during the day and following night. In thirty- 
six hours from the time that the bromide was first given he was walking 
about, feeling a little weak, and occasionally a slight twitch. Concerning 
this case there are several important points that it would be well to note : — 
1. The length of time that elapsed before the effect of the poison was 
manifest. 2. A very marked tolerance of opium. 3. Vomiting afforded 
great relief. 4. The antidotal power of bromide of potassium. The naked 
facts only are presented ; my professional brethren may draw their own in- 
ferences.” 
The Gastric and Intestinal Tubules. — These structures, in connection with 
their pathological relations, have been very carefully studied by Dr. Austin 
Flint, Professor of the Practice of Medicine in the Bellevue Hospital 
Medical College, U.S. We merely call attention to the memoir published 
