Loupiny III. 
G27 
ceived in it ; in most cases the sanguineous character of the fluid is 
conspicuous to the naked eye, and when examined under the 
microscope it is found crowded with red blood discs. 
2. The change next in importance as regards frequency, concerns 
the lungs. In sheep in an early stage of the disease the lungs show 
no conspicuous change, but when the disease is well established the 
lungs show lobular congestion with petechne, which, in the later 
phases, amounts to (red) consolidation of a large portion of a lobe, 
most commonly in the middle portion of the lungs. When the 
disease runs its full course and the animal is examined after death, 
the consolidation involves the greater part of one lung (middle and 
lower portion) or even both lungs. Such parts look dark red, are 
hepatised, and sink in water. On incision they are very juicy and 
yield much sanguineous fluid. In lambs the lung is always involved ; 
even in cases when the post-mortem examination is made a day 
after the animal showed the first symptom of the disease, one 
commonly finds the middle portion of one lung affected, being in a 
state of extreme congestion and red hepatisation. Pleural fluid, 
sometimes of sanguineous character, is present when the lung is 
involved, and the amount of this exudation is greater the more 
extensively the lung is affected. 
3. A further important change is noticeable in the heart and 
pericardium. In sheep this condition is always present except in 
the earliest phases ; in lambs it is present only to a small extent, 
and then only in the well-pronounced and later phases. Amongst 
the six lambs the cardiac change was absent in two, and was 
present only to a limited extent in the other four. The change is 
this : Haemorrhagic spots, patches and streaks on the endocardium 
of the right or left ventricle, or both ; in some cases the surface of 
the trabecuhe carnete being streaked with bloody patches ; the 
auriculo-ventricular valves of the right or left heart, or both, show 
the same hemorrhagic patches, and at the same time are slightly 
swollen ; the right auricle is occasionally swollen and glassy-looking 
in its visceral pericardium, and this appearance is very conspicuous 
in the visceral pericardium of the base of the ventricles. 
In sheep in later phases this condition amounts to a conspicuous 
gelatinous or myxoedematous infiltration ; the parietal pericardium 
in the well-pronounced cases shows this gelatinous infiltration to a 
remarkable extent, being not merely an cedematous but a true 
myxoedematous infiltration ; the same is the case in the connective 
tissue between the sternum and pericardium, extending in some 
pronounced cases through the cervical aperture of the thorax into 
the deep connective tissue of the neck. The amount of this myxoe- 
dematous change of the connective tissue, in the anterior portion of 
the thoracic cavity, is in some cases so great that the gelatinous 
material can be taken out almost by handfuls. The myxoedematous 
condition of the pericardium and mediastinal connective tissue did 
not occur in any of the lambs. Here only the hremorrhage into 
the auriculo-ventricular valves was noticed ; but in sheep the 
myxoedematous infiltration of the base of the ventricles, of the 
