Effects of Diet on the Uterus. 
13 
1906-7.] 
This change, which may be described as a fibrosis (compare fig. 7 with 
figs. 5 and 6), was most marked in animals fed from weaning on an ox- 
flesh diet, for periods of from four to five months ; in this group of animals 
none became pregnant, while controls from the same litters, fed on bread 
and milk, all had young. 
From these observations it seems justifiable to state : 
(1) The use of a non-pliysiological diet, e.g. exclusive flesh, rice, or 
porridge, induces, in the great majority of cases, a modification in the 
structure of the uterine mucous membrane. This modification consists in 
a diminution in the number of the large connective tissue type of cells, 
which appear to be important constituents in a physiologically active 
mucosa. 
(2) The structural change is most profound in animals fed from 
weaning on an exclusively flesh diet. In such animals the development of 
the uterus is also most interfered with. 
(3) The structural change in (2) is associated with sterility.* 
* The expenses of this research were in part defrayed by a grant from the Carnegie 
Trust. 
(. Issued separately February 11, 1907.) 
