1906-7.] Excessive Meat Diet and the Osseous System. 
5 
red blood corpuscles. Associated with this there is, in a number of cases, 
the presence in the bony ribs of nodules of cartilage, developed from the 
periosteum, with direct transformation of these cartilage cells into bone. 
It is noteworthy that, while the naked-eye appearances of the skeleton 
may closely simulate those present in advanced cases of rickets in the 
human subject, the microscopic appearances in the epiphysial junctions of 
long bones of meat-fed rats are quite distinct from those present in that 
disease. 
I have pleasure in expressing my indebtedness to Dr Dingwall Fordyce 
for much assistance in this investigation.* 
* The expenses of this research were defrayed by grants from the Moray Fund of the 
University, and from the Carnegie Trust. 
{Issued separately February 11, 1907.) 
