THE VALUE OF COMMERCIAL VACCINES AND 
BACTERINS AGAINST FOWL CHOLERA 
By 
L. VAN ES AND H. M'. MARTIN 
A great prevalence of the disease known as fowl cholera 
has naturally stimulated an interest in possible means of pre- 
vention and especially in those which may bring about a more 
or less lasting immunity. Attempts at immunizing against this 
disease date back to the very beginning of the era of modern 
bacteriology and immunology, and there is no doubt that many 
investigators succeeded in causing immunity in chickens by one 
method or other. Apparently, however, it has not yet been 
possible thru any of those methods to gain a solid footing and 
general dependability. Vaccines which were favorably reported 
by some failed utterly in the hands of others, so that on the 
whole no substantial advantage has been gained. 
Vaccines and bacterins are nevertheless constantly urged on 
poultry owners confronted with disease and the Experiment 
Station is frequently called upon to give an opinion on their 
value or to recommend any special preparation. 
In order to comply with those demands in an intelligent 
and impartial manner, we have thought it wise to make some 
experiments with the various preparations offered by the 
pharmaceutical trade in the hope that this may enable us to 
recommend all or any preparation for the relief of our poultry 
raisers. 
A search through the advertising pages of veterinary journals 
showed that in all six manufacturers offered vaccines and bac- 
terins against fowl cholera for sale and claimed for them im- 
munizing powers sufficient to warrant the expenditure of money 
on the part of poultry producers. 
