1901-2.] Prof. Schafer on Injection of Liver Cells. 
65 
On the Existence within the Liver Cells of Channels 
which can be directly injected from the Blood- 
Vessels. By E. A. Schafer. 
(Read February 3, 1902). 
In a series of papers dating from 1897, resumes of which are 
given in the Bulletin international de Vacademie des Sciences de 
Cracovie * Professor Browicz gives the results of observations on 
the liver cells, both in the normal state and in a pathologically 
altered condition, and draws from these observations certain 
important deductions. The most prominent fact which is recorded 
is the appearance (under normal conditions in the liver of the new- 
born child, and under pathological conditions in the adult human 
liver; under normal conditions, and after the intravenous injection 
of haemoglobin some hours prior to death, in the liver of the 
dog) of erythrocytes, singly and in groups, and of free haemoglobin 
and haemoglobin crystals, as well as brown pigment, in the form 
both of granules and crystalline clumps, within the hepatic cells, 
both in the nucleus and in the cytoplasm. After affirming the 
undoubted existence of intracellular biliary passages communicating 
with intercellular bile ducts, — which intracellular passages he 
regards, not as accidental and temporary vacuoles, but as preformed 
channels within the cells, — Professor Browicz states that his 
observations, especially the presence within the liver cells of 
* “Intracellular biliary passages in the liver cells,” March 1897 ; “On 
pathological conditions of the nucleus of the hepatic cell indicating that the 
nucleus is a secreting organ,” April 1897 ; “On the structure of the liver 
cell,” May 1897 ; “How and in what form is haemoglobin brought to the 
liver cells?” June 1897 ; “ On crystallisation phenomena in the liver cells,” 
April 1898; “On the intravascular cells in the hepatic capillaries,” April 
1898 ; “On microscopic appearances in the liver cells after intravenous 
injection of haemoglobin,” November 1898 ; “ Intussusception of erythrocytes 
by the liver cell and the appearances of the cells thereby produced,” July 
1899 ; “ Channels of nutrition in the liver cell — with a resume of the author’s 
results since 1897,” Jnly 1899 ; “ Structure of intra-acinous blood-capillaries 
and their relations to the liver cells,” May 1900. 
PROC. ROY. SOC. EDIN. — VOL. XXIV. 
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