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Proceedings of Poyod Society of Edinburgh. 
endemic in Ceylon, New Caledonia, Fiji, and Samoa; and it is met 
with amongst the Hindoo population of Pondicherry. In the West 
Indies it is endemic in San Domingo, Jamaica, Barbadoes, Martinique, 
Guadaloupe, Sta Lucia, and Dominica. It is found all over Brazil 
and in Guiana, and is said to he rather frequent at Punta Arenas 
in Central America. 
Remarks . — Yaws is distinctly a tropical disease, and the poison, 
whatever it may he, depends for its production on extreme heat 
and moisture; but although these factors would appear necessary 
for its production, there must be other causes, for in some countries, 
as in India for example, where the same temperature and moisture 
exist, yaws is unknown. Negroes chiefly suffer from its ravages, 
but no race is exempt, although it must be admitted that it attacks 
Europeans with comparative rarity. 
XII. Fungus Disease op India. 
(See Plate VIII. B.) 
Synon . — Madura Foot ; Mycetoma ; Morbus tuberculosos pedis ; 
Ulcusgrave ; Podelkoma ; Fr. Degenerescence endemique des os du 
pied; P^rical; Keerenugra. 
Definition . — A diseased condition of the hands and feet, occur- 
ring in India, characterised by enlargement and distortion of the 
affected extremity, due to thickening of the cutaneous tissues, with 
degeneration and subsequent fracture of the osseous structures. There 
are two varieties of this malady — one, the pale or ochroid form ; the 
other, the melanoid or dark form. 
This disease has been recognised since 1712, when Kampfer 
first called attention to it, but little definite was known about it 
until Goodfrey in 1846, and Vandyke Carter in 1860, investigated 
it thoroughly. In all probability, as Carter assumes, the disease 
is due to a parasite, but authorities still differ as to the nature of 
the parasite, and also as to the nature of the method by which it 
finds entrance into the hand or foot affected. It seems to be clear 
that it is not a constitutional disease, but the various theories which 
have been put forward as to its precise cause cannot be reconciled. 
Hindoos of all classes are affected by the disease. Mahommedans 
