118 Annual Report for 1893 from the Principal of the 
tion was obviously very painful, and there was marked emaciation 
in consequence. The only treatment adopted was the internal 
administration of iodide of potassium, and during the first month 
little if any improvement was observable. After that the animal 
began to eat better, the swelling of the jaw diminished in size, and 
the general condition improved. Since then improvement has been 
steady, and at the date of writing the cure might be pronounced 
complete, since the animal is fat, and the enlargement of the jaw 
has all but disappeared. The bullock will be kept under observation 
for some time longer, and finally submitted to post-mortem examina- 
tion, in order to see whether the cure is real or apparent. 
During the year a considerable number of tongues, jaws, &c., 
affected with actinomycosis have been examined in the Laboratory, 
and in one instance the facts connected with the development of 
the disease were of such an unusual nature as to warrant their 
being recorded here. 
In the month of July last Mr. F. L. Gooch, F.R.C.V.S., of 
Stamford, on three different occasions forwarded to the Laboratory 
pieces of tumours removed by him from yearling steers, with the 
history that all the animals of a lot of twenty-one had such tumours, 
and that he suspected they had all been infected with actino- 
mycosis by means of setons. Owing to the hot weather prevailing 
at the time the first tumour was so putrid as to be unfit for exami- 
nation when it arrived, but in the case of the other two microscopic 
examination showed the presence of actinomyces granules. The 
facts since communicated by Mr. Gooch are as follows : , The whole 
of the herd were reared on a farm on the borders of the Fen district, 
and in the autumn of 1892 they were sent to a farm in Deeping 
Fen, to be wintered in a straw-yard. During their stay here they 
were all setoned by an “empiric” as a preventive of Black Quarter, 
and they were brought back to the farm on which they had been 
reared about the beginning of May, at which time some of them were 
showing signs of enlarged shoulders, and two had large “ wens ” on 
the jaw. When Mr. Gooch was first called to see the animals (in 
July), he found that every one of them was affected in some degree. 
Some of the setons were still in position, and around the seat of 
operation there were small tumours, while a hard cord extended up 
from the dewlap to a firm tumour near the shoulder. Under com- 
bined surgical and medicinal treatment (iodide of potassium) all the 
animals subsequently recovered. The unusual seat of the disease, 
and the fact that every animal in the herd was affected, hardly 
admit of any other explanation than that the person who performed 
the setoning operation had, by some means or another, contaminated 
the wounds, probably by means of his hands or the material with 
which he dressed the setons. 
Detection of Glanders by the use of Mallein. 
The last Annual Report of the College contained a reference to 
glanders, and to an attempt which was being made to introduce the 
