360 DR. EVANS ON THE POISONED SPINES OF THE WEEVER FISH. 
Mouse, A., .02 grm. dried venom caused the death of a mouse 
from a dry necrosis at the site of inoculation in two days. 
During the day after injection, there was marked paralysis 
of the hind quarters, the injection having been made under 
the skin of the back. The large vessels in neck and axilla 
were engorged and the sinuses of the brain were full. 
Mouse, B., injected with .01 grm. dried venom, showed 
weakness of hind quarters two days after injection, and five 
days after, a small greenish area appeared on the skin at site 
of inoculation. The animal died seven days after the injection 
with similar local symptoms as described in A., but the brain 
sinuses were not so engorged. 
Guinea pig , .05 grm. intraperitoneal injection caused death 
in three hours. After preliminary pallor and convulsions, the 
animal became gradually weaker and showed paralysis of the 
hind quarters. After two hours the heart could not be felt 
beating, but catchy respirations continued for another hour. 
Postmortem. There was clotting in the superficial vessels, 
and general venous engorgement. 
INTRAVENOUS INJECTIONS. 
The results of experiments as illustrated by simultaneous 
tracings of carotid blood pressure and respiratory movements 
do not altogether agree with Briot’s statement that death, in 
the case of intravenous injections, is due to respiratory failure. 
The action appears to follow the course of that which occurs 
with most Snake venoms, i.e., a slightly preliminary rise, 
followed by a very rapid and deep fall in blood pressure. 
Experiment 1. Rabbit, weight 1,900 grms., anaesthetic 
ether. After an injection of .05 grm. dried poison, there was 
a fall in blood pressure lasting forty-five seconds. Then, after 
twenty seconds of irregular low pressure, the pressure gradually 
rose. After an interval of seven minutes, during which the 
cardiac pulsations had steadied down to a normal rate, 
a further .05 grm. of dried venom was injected into the femoral 
vein. Immediately the blood pressure fell rapidly for twenty 
seconds with almost imperceptible cardiac pulsations, and in 
