551 
1908 - 9 .] The Pathogenesis of Micrococcus melitensis. 
appears distressed, and the temperature rises to nearly 40° C. During the 
next few days the local lesion becomes soft, and fluctuation can be obtained. 
A few days later necrosis of the skin covering the tumour takes place, a 
slough separates, and thick creamy pus crowded with M. melitensis exudes 
from the abscess cavity, leaving an extensive ulcerating cavity. After a 
week or two, during which the exudation gradually becomes less in amount, 
healthy-looking granulations spring up, cicatrisation proceeds, and in about 
three weeks the animal appears perfectly normal as to temperature, and 
may even put on weight ; but in the course of the following weeks or 
