559 
1908-9.] The Pathogenesis of Micrococcus melitensis. 
days after infection ; while examination of the blood in the early stages of 
infection, of the urine later on, and later still, in the case of milch goats, of 
the milk, yields absolute evidence of the reality of infection, by the isolation 
CHART 11. 
Animal ...... horse 
Sex ...... female 
Dose . . . . . .25 milligrammes agar culture 
of the specific micro-organism. None of the experimental animals died as 
the direct result of the artificial inoculation. Consequently, I shall refer 
in detail only to some subcutaneous and cutaneous experiments which are 
of particular interest. 
Subcutaneous Infection . — Four normal healthy half -grown goats were 
