564 Proceedings of the Royal Society of Edinburgh. [Sess. 
Results of Post-mortem Examinations of Goats Experimentally Infected. 
No. 
Sex. 
Remarks. 
^ Duration of Infec- 
% tion or Period of 
Sf Observation. 
^ Presence of 
M. melitensis noted 
U During Life. 
Titre of Serum. 
Post-mortem Findings. 
M. melitensis present in 
Heart Blood. 
s’ 
O) 
a> 
r—H 
Ph 
m 
Kidney. 
Glands. 
CD 
D 
Inguinal. 
Mesenteric. 
1 
E 
Cutaneous inoculation 
3 
1 : 100 
+ 
+ 
0 
2 
M 
Subcutaneous inoculation . 
6 
— 
1 : 200 
— 
+ 
— 
+ 
— 
— 
3 
M 
55 55 
6 
— 
1 : 100 
— 
+ 
— 
+ 
+ 
— 
4 
F 
5? 55 
6 
... 
1 : 20 
— 
+ 
— 
— 
— 
0 
5 
F 
5 5 5 5 
6 
— 
1 : 20 
— 
+ 
— 
— 
- 
0 
6 
F 
5 5 55 
21 
— 
1 : 1500 
— 
+ 
— 
— 
+ 
0 
7 
F 
Feeding .... 
26 
— 
1 : 100 
- 
+ 
- 
+ 
- 
0 
8 
F 
55 .... 
37 
At 7 weeks 
1 : 20 
— 
— 
— 
- 
— 
9 
F 
Subcutaneous i noculation . 
39 
— 
1 : 20 
— 
+ 
— 
— 
— 
0 
10 
F 
Feeding .... 
41 
— 
1 : 10 
— 
— 
— 
— 
— 
0 
11 
F 
55 .... 
42 
— 
? 
— 
+ 
— 
— 
— 
0 
12 
F 
55 .... 
45 
At 13 weeks 
1 : 10 
— 
- 
— 
— 
— 
0 
13 
F 
55 .... 
45 
At 20 „ 
1 : 150 
— 
— 
— 
+ 
— 
+ 
14 
F 
55 .... 
49 
At 20 „ 
1 : 20 
— 
— 
— 
— 
— 
+ 
15 
F 
55 .... 
49 
— 
1 : 50 
— 
— 
— 
— 
— 
— 
16 
F 
55 .... 
53 
At 43 weeks 
1 : 160 
— 
— 
— 
— 
— 
0 
till killed. 
- =M. melitensis not recovered. + =M. melitensis recovered. 0 = Not examined. 
Post-mortem Examination of 5 Naturally Infected Milch Goats. 
Period of 
Observation. 
Weeks. 
M. melitensis recovered 
During Life from 
M. melitensis recovered Post-mortem from 
Urine. 
Milk. 
Titre of 
Serum. 
Heart 
Blood. 
Spleen. 
Glands. 
Udder. 
Mes- 
enteric. 
Inguinal. 
19 
1 : 20 
+ 
0 
19 
- 
+ 
1 : 20 
— 
— 
— 
— 
+ 
19 
- 
+ 
1 : 10 
— 
— 
— 
+ 
0 
43 
— 
+ 
1 : 160 
— 
— 
— 
+ 
+ 
56 
+ 
+ 
1 : 20 
— 
— 
— 
— 
0 
- =M. melitensis not recovered, -f- =M. melitensis recovered. O = not examined. 
The point of greatest practical importance that emerges from the study 
of laboratory infections of the goat is the appearance of M. melitensis in 
the milk. When the fluid has been systematically examined in experi- 
mental milch goats the appearance of the coccus has invariably been a late 
phenomenon. One goat, for instance, commenced to pass the micrococcus in 
