572 
Proceedings of the Royal Society of Edinburgh. [Sess. 
the exact date of inoculation could be fixed, the shortest period of incubation 
was 5 days, the longest 16 days, the average being just over 8 days (the 
exact duration being 5, 5, 5, 6, 8, 15, 15, and 16 days respectively). 
In those cases where the incubation period extended to 15 days, the 
accident which caused the infection was noted at the time, and strenuous 
efforts, by the liberal application of antiseptics, were made to reduce the 
probability of an attack of M. melitensis septicaemia. The lengthy incuba- 
tion period (16 days) in one case previously treated with M. melitensis 
vaccine would appear to indicate that some protection — although obviously 
inadequate — had been conferred as a result of the treatment. 
