573 
1908-9.] The Pathogenesis of Micrococcus melitensis. 
Cases of M. melitensis septicaemia in man present different features with 
almost every individual attacked, but may be grouped under one or other 
of the headings acute, subacute, and ambulatory, and may be briefly described 
as follows : — 
(1) Acute Form . — This type is extremely acute from the onset, and is 
initiated in the previously healthy by rigors, accompanied by a temperature 
of 38*5°, 40°, or 4T5° C. ; severe headache, often limited to the back of the 
CHART 20. 
DA 
fXS 
Titre 
Weight 
grms. 
°c. 
7 
z 
3 
6 
5 
6 
7 
8 
9 
70 
// 
/z 
73. 
77 
73 
76 
// 
78 
79 
ZO 
Z7 
zz 
Z3 
c> 
F. 
too 
80 
60 
60 
20 
0 
6Z 
67 
707 
706 
60 
705 
706 
/ 
• 
3© 
/ 
\ 
K 
A 
4 
703 
102 
\T 
r 
4 
V 
• 
7 
pfi 
M 
A 
f 
tin 
f V 
t 
I 
38 
[V 
L 
/ 
M S 
107 
100 
99 
98 
V 
•4 
Mae 
§ 
3T 
36 
\ 
97 
? Food Infection in Man. 
Type of infection ..... acute 
Result ....... death 23rd day of illness 
eyeball ; indefinite pains about the trunk and limbs, particularly in the 
back ; and general malaise. The face is flushed, the dorsum of the tongue 
is thickly coated with white fur, but pink and moist at the sides and tip, 
or more rarely dry, brown, glazed and cracked, and the breath offensive. 
Diarrhoea is not infrequently present during the first few days of the attack, 
but soon gives place to constipation. The pulse is strong and increased in 
frequency, though not usually in proportion to the temperature. The urine 
is diminished in amount, high in colour, and contains large quantities of 
uric acid and urates. This type of fever sometimes passes into the “typhoid ” 
